C07C323/42

Trifluoroethyl thioether (sulfoxide) substituted benzene compound and use thereof

The present invention belongs to the field of agricultural acaricides, and particularly relates to a trifluoroethyl thioether (sulfoxide) substituted benzene compound and use thereof. The compound has a structure as shown in general formula I: ##STR00001## The definition of each substituent in the formula is described in the specification. The compound of general formula I has excellent acaricidal activity and can be used to prevent and control various pest mites.

Trifluoroethyl thioether (sulfoxide) substituted benzene compound and use thereof

The present invention belongs to the field of agricultural acaricides, and particularly relates to a trifluoroethyl thioether (sulfoxide) substituted benzene compound and use thereof. The compound has a structure as shown in general formula I: ##STR00001## The definition of each substituent in the formula is described in the specification. The compound of general formula I has excellent acaricidal activity and can be used to prevent and control various pest mites.

Ketone inhibitors of lysine gingipain

The present invention provides compounds according to Formula I as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity probe compounds and methods for assaying gingipain activity are also described, as well as methods for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease.

Ketone inhibitors of lysine gingipain

The present invention provides compounds according to Formula I as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity probe compounds and methods for assaying gingipain activity are also described, as well as methods for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease.

DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME
20220017461 · 2022-01-20 · ·

Disclosed is a novel diamine compound comprising a structure in which diphenyl sulfide in a molecule is bonded through an amide bond to a phenyl ring substituted with an amine group. A polyimide film prepared by polymerizing the novel diamine compound exhibits improved mechanical and thermal properties and an enhanced refractive index.

DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME
20220017461 · 2022-01-20 · ·

Disclosed is a novel diamine compound comprising a structure in which diphenyl sulfide in a molecule is bonded through an amide bond to a phenyl ring substituted with an amine group. A polyimide film prepared by polymerizing the novel diamine compound exhibits improved mechanical and thermal properties and an enhanced refractive index.

PARG INHIBITORS AND METHOD OF USE THEREOF

Provided herein are, inter alia, compounds inhibiting poly(ADP-ribose) Glycohydrolase (PARG) in a cancer cell and methods of treating cancer using compounds of the invention.

KETONE INHIBITORS OF LYSINE GINGIPAIN

The present invention provides compounds according to Formula I as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity probe compounds and methods for assaying gingipain activity are also described, as well as methods for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease.