Described herein is a system including a catheter, an optical circuit, a pulsed field ablation energy source, and a processing device. The catheter includes a proximal section, a distal section, and a shaft coupled between the proximal section and the distal section. The optical circuit is configured to transport light at least partially from the proximal section to the distal section and back. The pulsed field ablation energy source is coupled to the catheter and configured to transmit pulsed electrical signals to a tissue sample. The processing device is configured to analyze one or more optical signals received from the optical circuit to determine changes in polarization or phase retardation of light reflected or scattered by the tissue sample, and determine changes in a birefringence of the tissue sample based on the changes in polarization or phase retardation.

Adjacent tissue layers can be accessed using a catheter device with a distal tip having a conductive portion including a first cutting feature and one or more projections extending from the first cutting feature towards an outer diameter of the distal tip. Electrical energy can be supplied to the conductive portion of the device to cut tissue. A stent can be delivered to form a fluid communication between the adjacent tissue layers.

A surgical instrument includes a shaft assembly having a distal end and an end effector at the distal end of the shaft assembly. The end effector includes a first jaw and a second jaw movably coupled relative to the first jaw for clamping tissue therebetween. The end effector also includes at least one lightbox for detecting the tissue. The at least one lightbox includes a housing having at least one optically transmissive surface configured to face the tissue. The at least one lightbox also includes at least one of an illuminating element or a light receiving element. The at least one of an illuminating element or a light receiving element is secured to the housing.

The present disclosure provides electroporation systems and methods of energizing a catheter for delivering electroporation. A catheter for delivering electroporation includes a distal section and an electrode assembly. The distal section is configured to be positioned in a vein within a body. The vein defines a central axis. The electrode assembly is coupled to the distal section and includes a structure and a plurality of electrodes distributed thereabout. The structure is configured to at least partially contact the vein. Each of the electrodes is configured to be selectively energized to form a circumferential ring of energized electrodes that is concentric with the central axis of the vein.

Various systems and methods for determining the composition of tissue via an ultrasonic surgical instrument are disclosed. A control circuit can be configured to monitor the change in resonant frequency of an ultrasonic electromechanical system of the ultrasonic surgical instrument as the ultrasonic blade oscillates against a tissue and determine the composition of the tissue accordingly. In some aspects, the control circuit can be configured to modify the operation of the ultrasonic electromechanical system or other operational parameters of the ultrasonic surgical instrument according to the detected tissue composition.

Balloon catheters with an elongate shaft defining a hollow body have an inflatable balloon at a distal end thereof. The balloon has a plurality of internal chambers that are inflatable to differing pressures. When inflated, the balloon has a generally hourglass shape having a neck between a distal end and a proximal end and a port at the neck that is in open communication the hollow body of the shaft and in open communication with an environment external to the balloon. The balloon catheter is inflated in a lumen of a patient to its hourglass shape with its proximal and distal ends in direct contact with normal endothelium juxtaposed to a target lesion with the neck of the balloon at the target lesion. A cutting tool is deployed through the port and an opening having a flap is cut into the target lesion and the plaque is removed thereof.

Methods, systems, devices, assemblies and apparatuses for treatment of hypertension in a patient using renal denervation. The therapeutic assembly includes an energy delivery element. The energy delivery element is configured to provide renal denervation energy to a nerve within a blood vessel of a patient. The therapeutic assembly includes a controller. The controller is coupled to the energy delivery element. The controller is configured to determine that the hypertension in the patient is orthostatic. The controller is configured to apply renal denervation energy to the patient using the energy delivery element.

A forceps includes a pair of jaw members movable relative to one another, one of the jaw members defining a blade channel therein configured to house a cutting mechanism. The cutting mechanism includes: a blade having camming slots defined along a length thereof and one or more blade springs operably associated therewith configured to bias the blade within the blade channel; and a blade cam including camming surfaces configured to operably engage the corresponding camming slots of the blade. The blade cam includes a proximal end operably coupled to an actuation rod configured to move the blade cam upon movement thereof. The actuation rod, upon movement thereof, moves the camming surfaces of the blade cam into engagement against the camming slots forcing the blade into the blade channel against the bias of the biasing spring to cut tissue therebetween.

The disclosed technology is directed to a treatment instrument having a vibration generating device and a handle for operation. The vibration generating device comprises a housing and a generator including a transducer disposed within the housing. The transducer generates vibration by using electric energy and a first electric contact disposed on the housing. A connector is rotatable about a predetermined rotational axis with respect to the housing of the generator. A coupler is disposed in the connector and having a second electric contact rotatable about the predetermined rotational axis with respect to the first electric contact in a state in which an electric connection of the second electric contact to the first electric contact is maintained. The connector further includes a conductive member forming a part of an electric path of a current that flows based on an operating input at an operating member provided on the handle.

An electrosurgical system can include an electrosurgical generator, a feedback circuit or controller, and an electrosurgical tool. The feedback circuit can provide an electrosurgery endpoint by determining the phase end point of a tissue to be treated. The electrosurgical system can include more than one electrosurgical tool for different electrosurgical operations and can include a variety of user interface features and audio/visual performance indicators. The electrosurgical system can also power conventional bipolar electrosurgical tools and direct current surgical appliances.