A system includes a laser catheter and a rotating optical member to receive a laser beam along an optical path and rotate to a selected position to redirect the laser beam from the optical path onto one or more selected optical fibers of a laser catheter, wherein a distal end of the laser catheter irradiates an endovascular structure.

The present disclosure relates to electrosurgical instruments for use in sealing various tissues. The instrument includes a housing having a shaft attached thereto and an end effector assembly attached to a distal end of the shaft, wherein the end effector assembly includes first and second jaw members attached thereto. The jaw members are movable relative to one another from a first position for approximating tissue to at least one additional position for grasping tissue therebetween. The jaw members have an elastomeric material disposed on an inner facing tissue contacting surface thereof with the elastomeric materials including an electrode disposed therein. The electrodes are offset a distance X relative to one another such that when the jaw members are closed about the tissue and when the electrodes are activated, electrosurgical energy flows through the tissue in a generally coplanar manner relative to the tissue contacting surfaces.

Embodiments of the present invention are directed to the treatment of hypertension, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pains, asthma, pulmonary arterial hypertension, and chronic obstructive pulmonary disease by delivering of an effective amount of formulations at desired temperature to target tissue. The formulations include gases, vapors, liquids, solutions, emulsions and suspensions of one or more ingredients. The temperature may enhance safety and efficacy of the formulations for the treatments. The amounts of the formulation and/or energy are effective to injury or damage the tissues to have a benefit of symptom relive.

An electrosurgical device having a pair of jaws, at least one electrode supported by one of the pair of jaws, and a sheet of expanded polytetrafluoroethylene positioned in covering relation to at least a portion of the at least one electrode. The sheet may have a porosity of between thirty and ninety percent. The sheet may have a plurality of pores with an average diameter of between 0.2 and 1.0 micrometers.

A surgical instrument with a rotatable and articulatable end effector. The end effector includes first and second jaws that are movable between an open position and a closed position by an axially movable drive member. The end effector is coupled to an elongate shaft such that the end effector is rotatable relative to the shaft about a shaft axis when the drive member is rotated. A releasable lock system is provided to selectively lock the end effector in a desired rotary position.

Methods, apparatuses, and systems for robotic insertion of a screw, a rod, or another component of a surgical implant into a patient are disclosed. Synchronous insertion of screws is performed by multiple surgical robots or a single surgical robot having multiple arms and end effectors. The movements of each robotic arm are coordinated into position in preparation of the insertion of multiple surgical implant components at the same time or in the same surgical step. The insertion of the surgical implant components is performed while monitoring the insertion progress. The insertion is completed autonomously or in coordination with a surgeon.

Methods, systems, devices, assemblies and apparatuses for treatment of hypertension in a patient using renal denervation. The therapeutic assembly includes an energy delivery element. The energy delivery element is configured to provide renal denervation energy to a nerve within a blood vessel of a patient. The therapeutic assembly includes a controller. The controller is coupled to the energy delivery element. The controller is configured to determine that the hypertension in the patient is orthostatic. The controller is configured to apply renal denervation energy to the patient using the energy delivery element.

Forceps including a housing, a first body, a second body and a drive shaft. The first body has a passageway extending therethrough. The drive shaft extending through the passageway and connected to the first body such that the first body and the drive shaft are slidable with respect to the housing to drive jaws located at a distal portion of the drive shaft between an open position and a closed position. The second body having a second passageway. The drive shaft extending through the second passageway such that the second body is guided by the drive shaft and is slidable relative to the first body and the drive shaft to displace a blade shaft between a retracted position and an extended position.

Provided herein are methods, devices and compositions for assessing neuromodulation efficacy based on changes in the level of one or more biomarkers in plasma or urine collected from a human subject following a renal neuromodulation procedure.

A forceps includes an end effector assembly with a first jaw having a tissue sealing surface and an electrode on the sealing surface, and a second jaw having a tissue sealing surface and an electrode on the sealing surface. The first jaw and the second jaw move between an open position and a closed position. The sealing surface of at least one of the first jaw and the second jaw has a flexible medial section and rigid lateral sections.