In general, devices, systems, and methods for control of one visualization with another are provided.

In general, devices, systems, and methods for control of one visualization with another are provided.

Methods, systems and devices for treating a patient include performing a first treatment to treat a first portion of tissue and performing a second treatment to treat a second portion of tissue. The second portion of tissue is treated at least twenty-four hours after the first portion of tissue is treated. In particular embodiments, the first portion of tissue includes duodenal tissue, and the second portion of tissue includes duodenal or other gastrointestinal tissue.

An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.

A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.

A light irradiating medical device comprising: a shaft extending in a longitudinal axis direction thereof and having a lumen extending in the longitudinal axis direction; a first tubular member disposed in the lumen of the shaft and rotatable about a rotation axis parallel to the longitudinal axis direction of the shaft, the first tubular member having a window located in a part of a peripheral wall of a distal portion; and a light guiding tool disposed in a lumen of the first tubular member and movable in the longitudinal axis direction, the light guiding tool including an optical fiber extending in the longitudinal axis direction, the optical fiber including a core, a cladding coating a radially outer portion of the core, and a cladding-absent portion located at a part of a distal portion of the core, and the window allowing passage therethrough of output light from the light guiding tool.

Embodiments of the present invention are directed to the treatment of hypertension, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pains, asthma, pulmonary arterial hypertension, and chronic obstructive pulmonary disease by delivering of an effective amount of formulations at desired temperature to target tissue. The formulations include gases, vapors, liquids, solutions, emulsions and suspensions of one or more ingredients. The temperature may enhance safety and efficacy of the formulations for the treatments. The amounts of the formulation and/or energy are effective to injury or damage the tissues to have a benefit of symptom relive.

Various embodiments provide an electrosurgical instrument comprising: a flexible coaxial transmission line arranged to convey microwave energy; a radiating tip portion connected at a distal end of the flexible coaxial transmission line and configured to receive the microwave energy, the radiating tip portion comprising: a distal coaxial transmission line for conveying the microwave energy; and a needle tip mounted at a distal end of the distal coaxial transmission line, the needle tip being arranged to deliver the microwave energy into biological tissue; and a heat sink mounted at an interface between the flexible coaxial transmission line and radiating tip portion. The heat sink is in thermal communication with a proximal end of the distal coaxial transmission line and configured to draw thermal energy from the radiating tip portion. Also, a maximum outer diameter of the radiating tip portion is smaller than an outer diameter of the flexible coaxial transmission line. An associated electrosurgical system is also disclosed.

A plasma instrument includes an elongated body defining a lumen therethrough, the lumen being in fluid communication with an ionizable media source; and a plasma applicator coupled to a distal portion of the elongated body. The plasma applicator includes: an active electrode configured to couple to an active terminal of a generator; and a corona electrode configured to couple to a return terminal of a generator. The plasma instrument also includes a switching element coupled to the corona electrode, the switching element configured to control at least one of resistivity or connectivity of the corona electrode to a generator.

Systems and methods for multi-modal imaging using an endoscope having an instrument channel, where the imaging is achieved without using the channel, are disclosed. The systems can include a multi-modal imaging paddle housing couple to a distal end of the endoscope. The housing can receive at least two imaging probes. The imaging probes can be an angle-resolved low-coherence interferometry probe (a/LCI) and an optical coherence tomography (OCT) probe. The housing can be scaled and positioned to be visible via the endoscope camera. The system and method can include locating the housing in a region of interest using the endoscope camera, acquiring OCT measurements to identify targets, and then acquiring a/LCI measurements at the identified targets.