A neuromodulation catheter in accordance with a particular embodiment includes an elongate shaft and a neuromodulation element operably connected to the shaft. The shaft includes a proximal hypotube segment at its proximal end portion and a jacket disposed around at least a portion of an outer surface of the hypotube segment. The jacket may be made at least partially of a polymer blend including polyether block amide and polysiloxane. The neuromodulation element includes a distal hypotube segment and a tubular jacket disposed around at least a portion of an outer surface of the distal hypotube segment. The jacket has reduced-diameter segments spaced apart along its longitudinal axis. The neuromodulation element further includes band electrodes respectively seated in the reduced-diameter segments and respectively forming closed loops extending circumferentially around the jacket.

A bipolar resectoscope (1) has a shaft (2, 2′) with an insulating insert (8) at its distal end (7). A working element (3) is mountable in the shaft (2, 2′) and a cutting electrode (4) is longitudinally displaceable in the shaft (2, 2′). The insulating insert (8) has an exposed conductive area of a neutral electrode (5, 5′). The area of the passive neutral electrode (5, 5′) exposed transverse to the longitudinal axis (34) forms an electrically conductive roof of the insulating insert (8, 8′). An inlet area (26) of the insulating insert (8, 8′) has an inner wall (38, 38′) with two opposing electrically conductive contact surfaces (39, 39′) of the neutral electrode (5, 5′) that are parallel to the longitudinal axis (33) and contact two parallel electrically conductive contact tubes (24) of a fork (26) and opening a cutting loop (25) of the cutting electrode (4).

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.

The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.

Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.

A laser delivery device may include a connector portion at a proximal end of the laser delivery device and an optical fiber connecting the connector portion to a distal end of the laser delivery device. The connector portion may include a capillary at least partially surrounding a proximal portion of the optical fiber, and the capillary may include dimples on at least a portion of a circumferential surface thereof.

A system and method for detecting relative location of a surgical laser fiber tip relative to a surgical laser target during a surgical laser procedure utilizes a spectrophotometer to detect radiation indicative of the relative location. For example, the detected radiation may indicate contact between the fiber tip and a stone being subjected to laser lithotripsy, so as to prompt the surgeon to withdraw the fiber tip from the stone and/or take other action to limit contact-induced erosion of the fiber tip, and to avoid saturation of the endoscope camera resulting from the flash that occurs following contact. In addition, the absence of any detected radiation by the spectrophotometer may be used to indicate that the stone is no longer present, or that the fiber tip is no longer aimed at the stone, prompting the operator to reposition the fiber and/or temporarily cease firing of the laser. The main surgical laser may be a pulsed Holmium laser, which is delivered to the target through the optical fiber together with a pulsed 532 nm aiming beam.

Embodiments of the disclosed technology relate to a bipolar electrosurgical device for a laparoscopic environment, as well as methods for the use of such a device. Embodiments of the device may include a set of opposing jaws comprising at least one bipolar electrode pair disposed thereon, the set of jaws configured to deliver radiofrequency energy to a target tissue. Embodiments of the set of jaws, when closed, may have a diameter no greater than about 5 mm. The device may further include a shaft with a diameter that may be no greater than about 5 mm. Each of the jaws has a tissue-facing surface of each jaw that may include a complementary self-aligning configuration with respect to the longitudinal axis of the other jaw. Embodiments of the device may further include a pinless rotation assembly formed from rotatably cooperative features of the first jaw and the second jaw that connect the jaws together and enable the jaw set to pivot between an open position and a closed position.

A method for the treatment of a patient for the purpose of lowering blood pressure and/or treating other medical conditions such as cardiac arrhythmias. A catheter having an ablation element is placed inside the body of a patient and is directed to a targeted location either on in the abdominal aorta where the right or left renal arteries branch from the aorta at or near the superior junction or ostia or on the inside of the inferior vena cava near the junction with the right renal vein or in the left renal vein at a position spatially near where the left renal artery branches from the abdominal aorta. Catheters designed for use in the method where these targeted locations are also disclosed and claimed.

An electrode assembly is provided. The electrode assembly includes a proximal end that is adapted to connect to an electrosurgical instrument including a housing defining a longitudinal axis therethrough and an electrosurgical energy source. A distal end includes a cutting electrode having a loop configuration configured to cut tissue. The distal end includes a return electrode operably disposed adjacent the cutting electrode. A dielectric shield is operably disposed between the cutting electrode and return electrode. The dielectric shield extending distally past the cutting electrode to hinder current flow to the return electrode when the dielectric shield, cutting electrode and return electrode are submersed in a conductive solution and the cutting electrode is energized, thereby concentrating current density at the cutting electrode.