Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.

Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, Q.sup.1, Q.sup.2, J, Y.sup.1, and Y.sup.2 are as defined in the disclosure.

Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound, N-oxide, salt or composition.

Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, Q.sup.1, Q.sup.2, J, Y.sup.1, and Y.sup.2 are as defined in the disclosure.

Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound, N-oxide, salt or composition.

Heterocycles having odoriferous ketone or odoriferous aldehyde groups may be suitable in compositions comprising washing agents, cleaning agents, cosmetic agents, air care agents, insect repellents, or combinations thereof where the heterocylces release the ketones and aldehydes during hydrolysis. The heterocycle(s) may have the formula:

##STR00001##

The present invention relates to compounds of the following formula (I), wherein: m represents an integer being equal to 0, 1, 2, 3, 4, 5 or 6, X represents a simple bond or a radical CHR.sub.1 wherein R.sub.1 represents:a hydrogen atom, ora linear or branched, possibly interrupted by up to 3 heteroatoms selected from O, S or N and/or possibly substituted, (C.sub.1-C.sub.12)-alkyl, R.sub.2, R.sub.3 and R.sub.4 represent independently from each other:a hydrogen atom, ora linear or branched (C.sub.1-C.sub.12-alkyl or (C.sub.1-C.sub.12)-acyl R5 represents:a hydrogen atom, ora linear or branched, possibly substituted, (C.sub.1-C.sub.13)-alkyi possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, R.sub.6 represents:a hydrogen atom, ora linear or branched possibly substituted (C.sub.1-C.sub.12)-alkyl, possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, for their use as antibacterial drugs for the treatment and/or the prevention of infection(s) caused by biofilm-forming bacteria.

The present invention relates to compounds of the following formula (I), wherein: m represents an integer being equal to 0, 1, 2, 3, 4, 5 or 6, X represents a simple bond or a radical CHR.sub.1 wherein R.sub.1 represents:a hydrogen atom, ora linear or branched, possibly interrupted by up to 3 heteroatoms selected from O, S or N and/or possibly substituted, (C.sub.1-C.sub.12)-alkyl, R.sub.2, R.sub.3 and R.sub.4 represent independently from each other:a hydrogen atom, ora linear or branched (C.sub.1-C.sub.12-alkyl or (C.sub.1-C.sub.12)-acyl R5 represents:a hydrogen atom, ora linear or branched, possibly substituted, (C.sub.1-C.sub.13)-alkyi possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, R.sub.6 represents:a hydrogen atom, ora linear or branched possibly substituted (C.sub.1-C.sub.12)-alkyl, possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, for their use as antibacterial drugs for the treatment and/or the prevention of infection(s) caused by biofilm-forming bacteria.

The invention relates to a crystalline form of [(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)-piperidine-3,4,5-triol, processes for the preparation thereof, pharmaceutical compositions containing such a crystalline form, and its use as a medicament, especially as glycolipid biosynthesis inhibitor.

The invention relates to a crystalline form of [(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)-piperidine-3,4,5-triol, processes for the preparation thereof, pharmaceutical compositions containing such a crystalline form, and its use as a medicament, especially as glycolipid biosynthesis inhibitor.

Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, Q.sup.1, Q.sup.2, J, Y.sup.1, and Y.sup.2 are as defined in the disclosure.

Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound. N-oxide, salt or composition.

Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, Q.sup.1, Q.sup.2, J, Y.sup.1, and Y.sup.2 are as defined in the disclosure.

Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound. N-oxide, salt or composition.