C07D213/127

Modulators of TMEM16A for treating respiratory disease

Compounds of general formula (I): ##STR00001##
wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, A, Z.sup.1, Z.sup.2 and Y are as defined herein are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.

Modulators of TMEM16A for treating respiratory disease

Compounds of general formula (I): ##STR00001##
wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, A, Z.sup.1, Z.sup.2 and Y are as defined herein are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.