C07D221/10

SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF

The present invention relates to six-membered ring benzo derivatives as a DPP-4 inhibitor and a use thereof. In particular, the present invention relates to a compound as shown in formula I, a pharmaceutical composition containing the compound as shown in formula I and a use of the compound in the preparation of drugs for treating DPP-4 related diseases or inhibiting DPP-4.

##STR00001##

Heterocyclic compound and organic light emitting device using same

The present application provides a hetero-cyclic compound capable of significantly enhancing lifespan, efficiency, electrochemical stability and thermal stability of an organic light emitting device, and an organic light emitting device containing the hetero-cyclic compound in an organic compound layer.

Tricyclic sulfones as RORγ modulators

There are described RORγ modulators of the formula (I), ##STR00001##
and formula (II) ##STR00002##
or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.

Tricyclic sulfones as RORγ modulators

There are described RORγ modulators of the formula (I), ##STR00001##
and formula (II) ##STR00002##
or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.

Organic light-emitting device

The present specification relates to an organic light emitting diode.

Organic light-emitting device

The present specification relates to an organic light emitting diode.

Compound used as autophagy regulator, and preparation method therefor and uses thereof

It is related to compounds used as autophagy modulators and a method for preparing and using the same, specifically providing a compound of general formula (I), or pharmaceutically acceptable salts thereof, which is a type of autophagy modulators, particularly mammalian ATG8 homologues modulators. ##STR00001##

NOVEL PHENANTHROLINE-BASED COMPOUND AND OPTOELECTRONIC DEVICE COMPRISING THE SAME
20230255108 · 2023-08-10 ·

The present invention relates to a novel compound for improving the photostability of an optoelectronic device, and more particularly, to a novel phenanthroline-based compound, a preparation method thereof, and an optoelectronic device including the same as a passivation layer. According to the present invention, the novel phenanthroline-based compound of Formula 1 is a novel compound in which an amine group side chain is introduced into the parent nucleus of phenanthroline, and is capable of being used in a solution process due to excellent solubility in a polar solvent, and simple introduction on an n-type semiconductor organic layer (e.g., an organic photoactive layer or an electron transport layer) as a passivation layer may bring about not only an increase in stability, but also an additional increase in efficiency such as an increase in open-circuit voltage or photocurrent.

Organic light-emitting device

The present specification relates to an organic light emitting diode.

Organic light-emitting device

The present specification relates to an organic light emitting diode.