C07D233/10

4-SUBSTITUTED AMINOISOQUINOLINE DERIVATIVES
20250084039 · 2025-03-13 ·

This invention relates to 4-substituted isoquinoline compounds and their derivatives and uses thereof for treatment of cancer, for example, acute myeloid leukemia.

4-SUBSTITUTED AMINOISOQUINOLINE DERIVATIVES
20250084039 · 2025-03-13 ·

This invention relates to 4-substituted isoquinoline compounds and their derivatives and uses thereof for treatment of cancer, for example, acute myeloid leukemia.

Polymorphic form of (-)-cibenzoline succinate
12486237 · 2025-12-02 · ·

The present invention relates to a crystalline form of ()-cibenzoline succinate. The present invention also provides a process for preparing ()-cibenzoline succinate and crystalline form thereof. The crystalline form of ()-cibenzoline succinate according to the present invention has low hygroscopicity, and excellent stability under accelerated conditions and long-term storage conditions, and may be stably maintained without a change in content thereof for a long period of time.

Polymorphic form of (-)-cibenzoline succinate
12486237 · 2025-12-02 · ·

The present invention relates to a crystalline form of ()-cibenzoline succinate. The present invention also provides a process for preparing ()-cibenzoline succinate and crystalline form thereof. The crystalline form of ()-cibenzoline succinate according to the present invention has low hygroscopicity, and excellent stability under accelerated conditions and long-term storage conditions, and may be stably maintained without a change in content thereof for a long period of time.

Method for preparing (−)-cibenzoline succinate

The present invention relates to a crystal form of ()-Cibenzoline succinate. In addition, the present invention relates to a method for preparing ()-cibenzoline succinate having a chiral purity of 99.9% or higher. Additionally, the present invention provides a method for preparing ()-cibenzoline succinate and a crystal form thereof.

Method for preparing (−)-cibenzoline succinate

The present invention relates to a crystal form of ()-Cibenzoline succinate. In addition, the present invention relates to a method for preparing ()-cibenzoline succinate having a chiral purity of 99.9% or higher. Additionally, the present invention provides a method for preparing ()-cibenzoline succinate and a crystal form thereof.