Patent classifications
C07D233/50
METHODS OF TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an -adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, acute, neuropathic and chronic.
Methods of treating α adrenergic mediated conditions
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an -adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, acute, neuropathic and chronic.
METHODS OF TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an -adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, acute, neuropathic and chronic.
Electronic Device and Compound
The invention relates to an electronic device comprising a compound having Formula (1): AB.sub.x (1), wherein A is a structural moiety that consists of at least two atoms and comprises a conjugated system of delocalized electrons, each B is independently selected from an imine functional group (1a), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 are independently selected from C.sub.1-C.sub.30 alkyl, C.sub.2-C.sub.30 alkenyl, C.sub.2-C.sub.3 alkinyl, C.sub.3-C.sub.30 cycloalkyl, C.sub.6-C.sub.30 aryl, C.sub.2-C.sub.30 heteroaryl, C.sub.7-C.sub.30 arylalkyl, C.sub.3-C.sub.30 heteroarylalkyl, the wave line represents a covalent bond to the imine nitrogen atom, G is in each group (1a) independently selected from a quarternary carbon atom and from a cyclopropenylidene structural moiety, x is an integer equal one or higher, preferably equal two or higher, and the lone electron pair of the imine nitrogen atom and/or the pi-electrons of the imine double bond of at least one group B is conjugated with the conjugated system of delocalized electrons comprised in the structural moiety A, with the proviso that two or more of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4 may be connected to form a ring that may contain also unsaturation and, if any of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4 comprises two or more carbon atoms, up to one third of the overall count of the carbon atoms in the substituent or in any ring formed by two connected substituents can be replaced with heteroatoms independently selected from O, S, N and B as well as to an electrically semiconducting material and a compound for use in the electronic device.
##STR00001##
Electronic Device and Compound
The invention relates to an electronic device comprising a compound having Formula (1): AB.sub.x (1), wherein A is a structural moiety that consists of at least two atoms and comprises a conjugated system of delocalized electrons, each B is independently selected from an imine functional group (1a), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 are independently selected from C.sub.1-C.sub.30 alkyl, C.sub.2-C.sub.30 alkenyl, C.sub.2-C.sub.3 alkinyl, C.sub.3-C.sub.30 cycloalkyl, C.sub.6-C.sub.30 aryl, C.sub.2-C.sub.30 heteroaryl, C.sub.7-C.sub.30 arylalkyl, C.sub.3-C.sub.30 heteroarylalkyl, the wave line represents a covalent bond to the imine nitrogen atom, G is in each group (1a) independently selected from a quarternary carbon atom and from a cyclopropenylidene structural moiety, x is an integer equal one or higher, preferably equal two or higher, and the lone electron pair of the imine nitrogen atom and/or the pi-electrons of the imine double bond of at least one group B is conjugated with the conjugated system of delocalized electrons comprised in the structural moiety A, with the proviso that two or more of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4 may be connected to form a ring that may contain also unsaturation and, if any of the substituents R.sup.1, R.sup.2, R.sup.3, R.sup.4 comprises two or more carbon atoms, up to one third of the overall count of the carbon atoms in the substituent or in any ring formed by two connected substituents can be replaced with heteroatoms independently selected from O, S, N and B as well as to an electrically semiconducting material and a compound for use in the electronic device.
##STR00001##
Methods of treating α adrenergic mediated conditions
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an -adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, acute, neuropathic and chronic.
Methods of treating α adrenergic mediated conditions
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an -adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, acute, neuropathic and chronic.
NOVEL CARBOXY LIGANDS AND USE THEREOF IN CATALYSTS
The invention relates to a carboxy ligand such as those defined via the general formula (I) specified in the following text. The invention additionally relates to a bismuth-containing catalyst such as those according to the general formula (II), wherein the bismuth-containing catalyst comprises carboxy ligands of the general formula (I). The invention additionally relates to a method for producing such a carboxy ligand and to a method for producing such a bismuth-containing catalyst. During the production of the carboxy ligand according to the invention, a precursor of a ligand according to the general formula (III) is likewise obtained according to the invention. The invention also relates to the use of such a bismuth-containing catalyst for producing compounds which contain a urethane group.
NOVEL CARBOXY LIGANDS AND USE THEREOF IN CATALYSTS
The invention relates to a carboxy ligand such as those defined via the general formula (I) specified in the following text. The invention additionally relates to a bismuth-containing catalyst such as those according to the general formula (II), wherein the bismuth-containing catalyst comprises carboxy ligands of the general formula (I). The invention additionally relates to a method for producing such a carboxy ligand and to a method for producing such a bismuth-containing catalyst. During the production of the carboxy ligand according to the invention, a precursor of a ligand according to the general formula (III) is likewise obtained according to the invention. The invention also relates to the use of such a bismuth-containing catalyst for producing compounds which contain a urethane group.
Epoxide functionalized polyaromatic feedstock and polymers derived therefrom
Epoxide functionalized polyaromatic feedstocks and processes for their preparation are described. The processes involve functionalizing polyaromatic hydrocarbon molecules and/or polyheterocyclic molecules present in petroleum or petrochemical streams with epoxide. The epoxide functionalized poly aromatic feedstock can be further treated so as to effect oligomerization or polymerization. The oligomers or polymers may be thermoplastic or thermoset materials and may find use in, for example, infrastructure applications, composites, fillers, fire retardants and 3-D printing materials.