Provided herein is a process for preparing a pyridazine amine compound of formula V, and a process for preparing dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof. Further, provided herein are dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof, wherein the amino group is an ethylamino group.

Compounds, methods of making the compounds and methods of using the compounds are generally described herein. The compounds are generally of formula R.sup.1R.sup.2NZnY LiY, wherein R.sup.1 and R.sup.2 are independently selected from H, aryl, heteroaryl containing one or more heteroatoms, alkyl, alkenyl, alkynyl, and silicon derivatives thereof; and each Y is independently selected from F, Cl, Br, I, CN, SCN, NCO, HalO.sub.3, HalO.sub.4, NO.sub.3, BF.sub.4, PF.sub.6, H, an alcoholate of formula OR.sup.5, a carboxylate of formula R.sup.5CO.sub.2; a thiolate of formula SR.sup.5, R.sup.5P(O)O.sub.2, SCOR.sup.5, SCSR.sup.5, O.sub.nSR.sup.5 and NO.sub.n, wherein n=2 or 3; wherein R.sup.5 is selected from substituted or unsubstituted aryls or heteroaryls containing 3 to 24 carbon atoms and one or more heteroatoms selected from B, O, N, S, Se, P, linear, branched or cyclic, substituted or unsubstituted alkyls, alkenyls, alkynyls or H; and wherein Hal is a halogen selected from Cl, Br and I.

Compounds, methods of making the compounds and methods of using the compounds are generally described herein. The compounds are generally of formula R.sup.1R.sup.2NZnY LiY, wherein R.sup.1 and R.sup.2 are independently selected from H, aryl, heteroaryl containing one or more heteroatoms, alkyl, alkenyl, alkynyl, and silicon derivatives thereof; and each Y is independently selected from F, Cl, Br, I, CN, SCN, NCO, HalO.sub.3, HalO.sub.4, NO.sub.3, BF.sub.4, PF.sub.6, H, an alcoholate of formula OR.sup.5, a carboxylate of formula R.sup.5CO.sub.2; a thiolate of formula SR.sup.5, R.sup.5P(O)O.sub.2, SCOR.sup.5, SCSR.sup.5, O.sub.nSR.sup.5 and NO.sub.n, wherein n=2 or 3; wherein R.sup.5 is selected from substituted or unsubstituted aryls or heteroaryls containing 3 to 24 carbon atoms and one or more heteroatoms selected from B, O, N, S, Se, P, linear, branched or cyclic, substituted or unsubstituted alkyls, alkenyls, alkynyls or H; and wherein Hal is a halogen selected from Cl, Br and I.

Primarily, the present invention relates to compounds of the formula (I) defined below and to their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The present invention also relates to herbicidal or plant growth-regulating compositions comprising one or more compounds of the formula (I). Moreover, the present invention relates to processes for preparing the compounds of the formula (I).

Primarily, the present invention relates to compounds of the formula (I) defined below and to their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The present invention also relates to herbicidal or plant growth-regulating compositions comprising one or more compounds of the formula (I). Moreover, the present invention relates to processes for preparing the compounds of the formula (I).

Disclosed are mild temperature (e.g., from 0 to 80 C.) S.sub.NAr fluorinations of a variety of halide and sulfonate substituted aryl and heteroaryl substrates using NMe.sub.4F.

A process for the preparation of compound of formula I is provided:

##STR00001##

where R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the description.

The present invention belongs to the technical field of pesticides, and in particular relates to a pyridazinol compound, a derivative thereof, a preparation method therefor, a herbicidal composition and the use thereof. The pyridazinol compound is as represented by general formula I, ##STR00001## wherein X represents ##STR00002##
and the ring is an unsubstituted or substituted aryl or unsubstituted or substituted heterocyclyl containing a carbon atom at the 1-position; Y represents haloalkyl; and Z represents halogen, cyano, hydroxy, etc. The derivative refers to an agriculturally acceptable derivative of the hydroxyl group at the 4-position of the pyridazine ring in the general formula I, including a salt, an ester, an oxime, a hydroxylamine and an ether derivative, etc. The compound, the derivative thereof and the composition thereof have good herbicidal activity and crop safety.

The present invention relates to cyclopropyl-(hetero)aryl substituted ethylsulphonyl-pyridine derivatives of formula (1) ##STR00001##
wherein the variables are as defined in the description and in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in animals.

Disclosed are pnictogen-containing heterocyclic compounds of Formula (I) ##STR00001##
Each of R.sub.1, the heterocyclic ring H, A.sup.+, LG, and X.sup. is defined herein. Also provided are methods of modifying a substrate using such a compound, conjugated biomolecules thus modified, and pharmaceutical compositions containing one of the conjugated biomolecules.