C07D307/12

New Anionic Surfactants And Detergents And Cleaning Agents Containing Same

An anionic surfactant of general formula (I) in which n and m are, independently of one another, numbers from 0 to 17 and 2<n+m<20, and X.sup.+ is a charge-balancing cation. The invention also relates to a production method by way of: the acid-catalysed reaction of 2,5-bis(hydroxymethyl) tetrahydrofuran with an alkene having 5 to 22 C atoms in equimolar amounts, at an increased temperature; subsequent sulphation with a sulphating agent; and optional neutralisation by a subsequent reaction with

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X.sup.+OH.sup.− or X.sup.+.sub.2CO.sup.2−.sub.3, where X.sup.+ is an alkali metal cation or a group N.sup.+R.sup.1R.sup.2R.sup.3, in which R.sup.1, R.sup.2 and R.sup.3 are, independently of one another, hydrogen, an alkyl group with 1 to 6 C atoms, or a hydroxyalkyl group with 2 to 6 C atoms. Detergents or cleaning agents containing the surfactant, and the use of same to improve the performance of the detergents or cleaning agents, are also disclosed.

Intermediate for preparing eribulin mesylate and process for preparing the same

The present invention relates to a process for preparing a compound of formula (6) which is an intermediate for the preparation of eribulin mesylate with high yields and high purity, and an intermediate therefor.

Intermediate for preparing eribulin mesylate and process for preparing the same

The present invention relates to a process for preparing a compound of formula (6) which is an intermediate for the preparation of eribulin mesylate with high yields and high purity, and an intermediate therefor.

OLEIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION OR FOOD COMPOSITION COMPRISING SAID OLEIC ACID DERIVATIVES, AND THEIR USES

Disclosed is an oleic acid derivative including a hydrophobic part C17H33 linked to a particular polar head part “A”, especially for use as a medicament, for instance, for the treatment of a disorder caused by the GPR120 receptor and/or the CD36 receptor, including administering to a subject in need thereof a therapeutically effective amount of the oleic acid derivative or of the pharmaceutical composition. Also disclosed is the use of the oleic acid derivative as a food composition.

Series of Skin-Whitening (Lightening) Compounds

The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

Series of Skin-Whitening (Lightening) Compounds

The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

Series of Skin-Whitening (Lightening) Compounds

The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

Series of Skin-Whitening (Lightening) Compounds

The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

A LUBRICANT COMPRISING 2,5-(BISHYDROXYMETHYL) TETRYHYDROFURAN DIALKANOATES

A lubricant comprising 2,5-(bishydroxymethyl) tetryhydrofuran dialkanoates This invention relates to a lubricant comprising a THF ester of the formula (I) as defined below. This invention further relates to a use of the THF ester as lubricant; and to a method for reducing friction between moving surfaces comprising the step of contacting the surfaces with the lubricant or with the THF ester.

A LUBRICANT COMPRISING 2,5-(BISHYDROXYMETHYL) TETRYHYDROFURAN DIALKANOATES

A lubricant comprising 2,5-(bishydroxymethyl) tetryhydrofuran dialkanoates This invention relates to a lubricant comprising a THF ester of the formula (I) as defined below. This invention further relates to a use of the THF ester as lubricant; and to a method for reducing friction between moving surfaces comprising the step of contacting the surfaces with the lubricant or with the THF ester.