Patent classifications
C
CHEMISTRY; METALLURGY
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C07
ORGANIC CHEMISTRY
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C07D
HETEROCYCLIC COMPOUNDS
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333/00
Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
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C07D333/50
condensed with carbocyclic rings or ring systems
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C07D333/52
Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
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C07D333/62
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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C07D333/68
Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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C07D333/68

MODULATORS OF RAR-RELATED ORPHAN RECEPTORS (RORs)
20220000864 · 2022-01-06 ·

The invention encompasses the novel class of compounds represented by the Formula (I), (II), (III) and (IV) below, which are modulators of RORγt:

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The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing autoimmune diseases and antibody mediated rejection in a patient in need thereof.

THIOPHENE HSD17B13 INHIBITORS AND USES THEREOF
20230278978 · 2023-09-07 ·

Described herein are HSD17B13 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of liver disease, metabolic disease, or cardiovascular disease, such as NAFLD or NASH, or drug induced liver injury (DILI).

INHIBITORS OF MICROBIALLY INDUCED AMYLOID
20230113225 · 2023-04-13 · ·

The present disclosure provides compounds useful for the prevention of amyloid formation and the treatment of amyloid related disorders, including synucleopathics such as Parkinson's Disease.

INHIBITORS OF MICROBIALLY INDUCED AMYLOID
20230113225 · 2023-04-13 · ·

The present disclosure provides compounds useful for the prevention of amyloid formation and the treatment of amyloid related disorders, including synucleopathics such as Parkinson's Disease.