Described herein in part are silanol based therapeutic payloads comprising a silanol terminus, a divalent spacer moiety, and a drug moiety capable of effecting a target cell or tissue.

Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Formula (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder. ##STR00001##

Reactive poly(fluoroalkyl-functional siloxane) oligomers, method of making the same, and compositions comprising the same are shown and described herein. The reactive poly(fluoroalkyl-functional siloxane) oligomers are is derived from a hydrolysable fluoroalkyl-functional silanes. Coating compositions comprising reactive poly(fluoroalkyl-functional siloxane) oligomer(s) may be used to form a coating or a film on a substrate and impart hydrophobic and/or oleophobic properties. The reactive poly(fluoroalkyl-functional siloxane) oligomer are more hydrophobic and oleophobic and show better chemical resistance than the hydrolysable fluoroalkyl-functional silane.

The invention provides a composition and method for improving the selectivity of nitride etching versus oxide etching and can be used with conventional phosphoric acid wet etch compositions. The invention describes additives that serve to inhibit silicon, oxides, and related compounds regrowth (i.e., redeposition) on the silicon oxide surface. In certain embodiments, the invention provides certain amino-substituted aryl compounds which are bound to a tri-alkoxy silane.

Provided herein are stationary phase compositions comprising a chromatographic surface of porous or non-porous core material comprising a surface modifier for use in chromatographic separations.

An elastomeric composition is based on at least a diene elastomer, an inorganic filler as reinforcing filler and a monohydroxysilane polysulfide as coupling agent of formula (I): (HO)(R.sup.1).sub.2SiCH.sub.2(R.sup.2)CHZS.sub.xZHC(R.sub.2)CH.sub.2Si(R.sup.1).sub.2(OH) (I), in which: each R.sup.1 represents a monovalent hydrocarbon group having from 1 to 18 carbon atoms and can be the same or different from one another; each R.sup.2 represents a monovalent hydrocarbon group having from 1 to 4 carbon atoms and can be the same or different from one another; each Z represents a divalent hydrocarbon bonding group comprising from 1 to 16 carbon atoms can be the same or different from one another; and x is an integral or fractional number greater than or equal to 2.

The present invention provides a method for producing a silanol compound capable of efficiently producing a silanol compound. The method for producing a silanol compound includes a proton exchange step of forming a silanol compound having a structure represented by following formula (c) by reacting a silicate having a structure represented by following formula (a) with an acidic compound having an acid dissociation constant pK.sub.a of 1 to 20 in dimethyl sulfoxide (DMSO).

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(In formula (a), Q.sup.i+ represents an i-valent cation and i represents an integer of 1 to 4).

An electrolyte additive, an electrolyte, and a lithium-ion battery, where the electrolyte additive has a structure shown in formula (I):

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The electrolyte additive has both a film-forming property and the property of inhibiting the rise of acidity and chromaticity of the electrolyte, thereby effectively improving the cycle performance of the battery.

The disclosed technology relates to materials for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in the diagnosis and/or detection of chronic or infected wounds based measurement of pH. Additional disclosure relates to methods of characterizing wounds based on pH of wounds or wound fluids and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Provided herein are stationary phase compositions comprising a chromatographic surface of porous or non-porous core material comprising a surface modifier for use in chromatographic separations.