The present invention relates to a pen for the treatment of dermatological disorders, such as warts and the like, by means of a coolant. The pen includes a distal part having a holder for the storage of a coolant and a proximal part with an applicator for the administration of the coolant to the dermatological surface for treatment. These parts extend axially and are in coolant communication by means of a coolant passage in the proximal part, in which a valve body is provided for closing off and/or opening the passage. The passage is provided with at least one bypass for the coolant. In addition, the invention relates to a method for the administration of the pen.

The present disclosure relates generally to the field of energy transfer mapping, including fixtures with two-dimensional and three-dimensional sensor arrays. In particular, the present disclosure relates to devices and methods for mapping of energy transfer from and/or to an instrument inserted within and/or into body tissue, including the depths and patterns of penetration and/or amounts of energy transfer to and/or from an instrument delivered within biological tissue or materials that mimic biological tissue, including within fixtures with three-dimensional temperature sensor arrays configured to simulate anatomical geometries such as the gastrointestinal (GI) or respiratory tract.

Disclosed herein are methods of treating skin disorders or relieving dermatological symptoms using precision cooling technology.

A system for accessing extra articular lesions or abnormalities or intra osseous lesions or abnormalities or bone marrow lesions using intra articular localization has a guide, an arm, a pair of attachment assemblies and a tubular sleeve. The guide component has a first portion and a second portion. The first portion has a first slotted opening extending a length from a first end. The second portion has an arcuate curvature extending from the first portion to a second end of the guide component with an elongated second arcuate slot in the second portion. The first attachment assembly is configured to be movably adjustable within the length of the first slotted opening. The second attachment assembly is configured to be movably adjustable along the elongated second arcuate slot.

Disclosed herein is a system for creating an injectable and flowable cold slurry, the system comprising a housing; a mount operatively connected to the housing configured to accept a container; a first motor configured to move the mount from a first position to a second position; a second motor; and a drive shaft in communication with the second motor, wherein the drive shaft is configured to rotate to cause an internal volume of the container to be transformed into the injectable and flowable cold slurry.

The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to devices and methods to convey fluid delivered from a delivery catheter. Exemplary catheters are disclosed which include fluid distribution devices for delivery of fluid and delivery of pass-through medical instruments, such as cryodecompression tubes, within body lumens.

A focused treatment tip (FTT) for controlling the evaporation rate and providing targeted delivery of low temperature liquified gases for contact with living tissue includes a contoured body. When filled with liquified gas, the device insulates the gas from waste heat sources, such as the surrounding environment. The device can control the evaporation rate of the liquified gas at the treatment site. The controlled evaporation rate affects the rate of heat transfer from the treated tissue allowing for controlled exposure times and desired outcomes. The device can be used with various application tips to further define the target tissue area to be treated while minimizing collateral damage to surrounding tissue and isolating the gas within the contoured body and focusing heat transfer to the desired treatment area. The device may use transparent materials that make the treatment visible to the operator while the liquified gas is evaporating.

Present disclosure provides a cooling device with safety features and methods for controlling temperature of the cooling device for safe cooling of target surface.

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.

Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.