An apparatus for performing cryosurgery, especially suited for the sacroiliac joint. The apparatus includes a first expansion tube having a first length; a second expansion tube having a second length, wherein the second length is longer than the first length; a first supply tube supplying a cooling agent to the first expansion tube; a second supply tube supplying another cooling agent to the second expansion tube; and a drain tube for removing cooling agents from an enclosed working part, wherein the first expansion tube supplies the cooling agent to a first portion of the working part, the second expansion tube supplies the another cooling agent to a second portion of the working part, the working part further including a tip; wherein the first expansion tube and the second expansion tube are positioned inside a casing.

Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated.

An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes near the distal ends of the needles allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media.

A cryosurgical instrument includes a feed line for conveying fluid into an expansion chamber. The feed line has a capillary line section that terminates in the expansion chamber and forms an aperture for the fluid to undergo the Joule-Thomson effect. The flow cross-section of the feed line decreases in at least one transition section of the feed line in the form of a funnel. Following each transition section there preferably follows a step section, in which latter section the flow cross-section is preferably largely constant. The last step section is preferably formed by the capillary line section. Due to the acceleration of the fluid in the transition sections and the abating of pressure fluctuations in the capillary tube section and, optionally in the additional step sections, the expansion range in the expansion chamber is increased, without impeding the backflow of the expanded gas out of the expansion chamber.

An endoscopy device is configured with a flexible cannula or tube for nasal insertion and has multiple parallel and adjacent lumens that provide sub-chambers configured to provide means to diagnose and treat Barrett's esophagus, such as by spray cryo-therapy with no further insertion of tubes. The lumens are configured to impart a small diameter with sufficient flexibility for nasal insertion into a patient's esophagus and accommodate a means any treatment modality. In the case of cryo-therapy, a lumen provides gas pressure relief, and is along the tube, with separate lumens for the delivery of a liquid freezing agent and an imaging means, which includes a source of illumination. Outer lumens may support guide wires used to steer the tube tip and aim the camera to determine the where to immobilize tip before the start of the treatment and/or to correct strictures formed in prior procedures.

The present disclosure relates to vision preservation systems for medical devices, such as cryospray devices for use with endoscopes. Exemplary embodiments provide a distal attachment in the form of a shroud or cap that mounts to the end of a flexible endoscope. A purging fluid supply mechanism is provided along the length of the endoscope, providing a channel for purging fluid, such as gas, to communicate between the endoscope tip and an external gas supply. The cap or shroud assembly incorporates a lens clearing flow field adjustment mechanism, such as nozzles, designed to direct warm (room temperature or higher) purging fluid across a lens at the scope tip. Another flow deflection mechanism, such as a guide or nozzle, may be included with the cap to direct purging fluid at an angle away from the lens. Gas, as an example, directed across and toward the lens purges moisture to avoid condensation on the lens and shears debris and bodily fluids away from the field of view. Gas directed or deflected by a guide away from the lens serves the purpose of keeping incoming particles and fluid droplets (e.g. spatter) from impacting on the lens cover. The cap and shroud are designed to avoid entraining moist air from the body cavity or lumen being treated.

Mechanical biomimicry translator. Epidermal lesion-removal triage-platform. Present invention cryotreats humanity suffering from benign basal-cell to aggressive, malignant, oncological lesions. Hand-held, artisan-styled monoframe. Prosthetic Blitzkrieg processing. Dermatology-tool.

Deployment eviscerates common histological abnormalities. Holographic Skeletal-Reflex Exoframe. Clinical. Metered. Structured. 360° rotate/ablate. Backbone. Glide-rails. Asymmetrical, gain-of-function; filtration-membrane.

Ground-zero; mobile directed-energy-matrix. Level-2 Spec-Ops-7. Digital encoder modulates/dispenses 3.sup.rd party biologics. Multi-factor authentication; oncological, epidemiological, gynecological; Gender-balanced. L.G.B.T.Q.I.A+ compatible. Agnostic. Mercy-Aid. NGO.

Rapid-Defense, Rapid-Offense-Procedures. De-risking cryodestruction. Multi-mission capable; first-aid, mobile family-medicine; medical-tourism. Pocket-Sherpa form-factor. Panoramic lesion harvesting. Recyclable.

Essential acute-care; lowering patientcare costs. Inclusion, diversity, equity, action. Uncompromising mitigation strategy. Comprehensive menu, human-performance enhancements democratizing open-source, Krieger-Amulet-TaaS®. Plug and play cold-fusion cryosurgery. Interdiction-Consumer-Empowerment. Humanitarians without borders. Patient-Lives-Matter.

A cryosurgery system for application of medical-grade liquid nitrogen to a treatment area via a small, low pressure, open tipped catheter. The system includes a console, including a touch panel computer, a cryogen module, a suction module and an electronics module, and a disposable spray kit. Features include optional low cryogen flow setting to reduce the cryogen flow rate by 50%, improved cryogen flow consistency reducing pressure pulses and peaks, an integrated suction pump for improved consistency and self-checks, specified vent tube areas and corresponding maximum expected pressures during cryospray procedure; optional pressure sensing capability to monitor pressure during a treatment, and novel catheter designs of multilayer and flexible construction providing a variety of spray patterns.

The present disclosure provides a method for treating clinical or pre-clinical skin damage in a skin field of a subject, wherein the skin field has been allocated a skin cancerization field index (SCFI) score of at least 1 as determined by a process comprising the steps of: (i) assessing the number of keratoses in the skin field; (ii) assessing the thickness of the thickest keratosis in the skin field; and (iii) assessing the proportion of the field affected by clinical or subclinical skin damage. Based on the assessments made in (i), (ii) and (iii) the subject is optionally treated by at least one of (a) freezing one or more lesions, (b) shaving, curetting or surgically removing one or more lesions, (c) applying a topical treatment for actinic keratosis, basal cell carcinoma or squamous cell carcinoma, and (d) radiation therapy.

A system for morcellating tissue within a body cavity is provided. The system includes a bag guide having a tubular body with proximal and distal ends, the distal end including a flange, a morcellator including an enlarged mouth for receipt within the flange of the bag guide, and a specimen bag receivable between the flange of the bag guide and the enlarged mouth of the morcellator. Also provided is a method of morcellating tissue within a body cavity.