A method and system for automated and semi-automated predictable, consistent, safe, effective, and lumen-specific and patient-specific cryospray treatment of airway tissue in which treatment duration is automatically set by the system following entry of patient information and treatment location information into the system by the user, and treatment spray is automatically stopped by the system when the automatically selected treatment duration has been achieved as determined by the system.

The invention disclosed here generally relates to devices that can modify a property of a nerve. Specifically, the subject invention is contemplated to modify the posterior nasal nerve signal conduction in such a way so as to reduce the signals transmitted to the nasal cavity. Reduction or interruption of the nerve signals results in the reduction of the distal organ activity. In particular, embodiments of the present invention allow for increased lateral contact or apposition of the target tissue region having at least one posterior nasal nerve with the end effector surface by lateral and/or longitudinal translation of the end effector relative to the surgical probe shaft. This improved lateral surface contact has several benefits, including improved patient outcomes and patient safety as the end effector is adequately in contact with target tissue for subsequent ablation therapy.

An ablation device comprising an ablation applicator adapted for ablating material from an object upon delivery of an ablation medium to the ablation applicator in an ablation mode, an ablation medium supply line adapted for supplying the ablation medium to the ablation applicator in the ablation mode, an ablation medium drain line adapted for draining the ablation medium received from the ablation applicator in the ablation mode, and a closure mechanism adapted for selectively enclosing a predefined volume in a fluidic path upon operating the ablation device in a no-flow mode or upon detecting a leak in the fluidic path, the fluidic path including the ablation applicator and being defined between the ablation medium supply line and the ablation medium drain line.

A surgical instrument includes a first shaft, a second shaft, and a hinge. The first shaft includes a proximal handle and a distal jaw member. The second shaft includes a first segment that has a proximal handle and a second segment that has a distal jaw member. One of the first and second shafts is pivotal relative to the other to pivot the jaw members between an open configuration where the jaw members are spaced relative to one another and an activatable configuration where the jaw members are closer to one another and suitable for applying electrosurgical energy to tissue disposed therebetween. The hinge couples the first and second segments to one another. The first and second segments have a straight configuration where the first and second segments align with a longitudinal axis and a pivoted configuration where the second segment is disposed at an angle relative to the longitudinal axis.

The present invention generally relates to improved medical devices, systems, and methods. In many embodiments, devices, systems, and methods for locating and treating a target nerve with integrated cold therapy and electrical stimulation systems are provided. For example, nerve stimulation and cryoneurolysis may be delivered concurrently or alternately with the cryo-stimulation device. In some embodiments, the device may be operated by a single operator or clinician. Accordingly, embodiments of the present disclosure may improve nerve targeting during cryoneurolysis procedures. Improvements in nerve localization and targeting may increase treatment accuracy, physician confidence in needle placement during treatment, and clinical efficacy and safety. In turn, such improvements may decrease overall treatment times, the number of repeat treatments, and the re-treatment rate. Further, additional improvements in nerve localization and targeting may reduce the number of needle insertions, applied treatment cycles, and may also reduce the number of cartridge changes.

A treatment system includes a magnetic sensor configured to detect a biomagnetic field generated by a living body to be treated, a catheter configured to be inserted into the living body, an image information processor programmed to generate a combined image including a first image expressing a strength of the biomagnetic field and a second image expressing a position of the catheter, by using biomagnetic field information output from the magnetic sensor and position information of the catheter inserted into the living body, and a display configured to display the combined image.

An ablation device comprising an ablation applicator adapted for ablating material from an object upon delivery of an ablation medium to the ablation applicator in an ablation mode, an ablation medium supply line adapted for supplying the ablation medium to the ablation applicator in the ablation mode, an ablation medium drain line adapted for draining the ablation medium received from the ablation applicator in the ablation mode, and a closure mechanism adapted for selectively enclosing a predefined volume in a fluidic path upon operating the ablation device in a no-flow mode or upon detecting a leak in the fluidic path, the fluidic path including the ablation applicator and being defined between the ablation medium supply line and the ablation medium drain line.

The apparatus and method includes a proximal balloon subsystem including a proximal balloon positionable to a selected first location within a blood vessel to be ablated. A distal balloon subsystem including a distal balloon is positionable to a selected second location within the blood vessel to be ablated. An ablating subsystem including an ablating element is configured to be positioned between the proximal balloon and the distal balloon within the blood vessel to be ablated. An evacuation port is configured to evacuate fluid between the proximal balloon and the distal balloon.

A cryoprotectant for use with a treatment device for improved removal of heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cryoprotectant is a non-freezing liquid, gel, or paste for allowing pre-cooling of the treatment device below 0 C. while preventing the formation of ice thereon. The cryoprotectant may also prevent freezing of the treatment device to the skin or ice from forming from moisture seeping out from the skin. The cryoprotectant may further be hygroscopic, thermally conductive, and biocompatible.

A mapping catheter comprises a flexible shaft having a proximal end and an opposite distal end, and an expandable mapping element attached to the distal end of the shaft. The expandable mapping element is configured to self-expand from a collapsed configuration to an expanded configuration. The expanded configuration is defined by a proximal portion extending from the distal end of the shaft and forming a proximally-facing concave recess, an intermediate portion extending distally from the proximal portion and defining a maximum diameter of the mapping element when in the expanded configuration, and a distal portion having a conical shape with a distal portion diameter that decreases in a direction distally of the intermediate portion. The mapping element further includes a plurality of electrodes located in one or both of the intermediate portion or the distal portion.