Methods and devices described herein facilitate improved treatment of body organs.

A probe and method of using a probe are disclosed. The probe may comprise a first member, a tip, a second member, and a third member. The first member may have a first and second end portions. The tip may be configured to engaged to the first member at the second end portion. The second member may be configured to extend and be positioned within the first member. The third member may be configured to be disposed outward of the second member along at least a portion of the second member, engage an inner surface of the first member, and define to least one passage between the third member and the first member. The probe may be coupled to a fluid supply and return, and fluid may flow within the probe, including within the passage defined between the first and third members.

A method in which a nerve associated with a spasticity in a limb of a patient may be identified. The cryogenic cooling needle may be inserted through a skin surface. The cryogenic cooling needle may be positioned to a target tissue such that the distal end of the cryogenic cooling needle is proximate to the nerve by bending the needle, wherein the needle has varying stiffness at a proximal portion and a distal portion. A treatment cycle may be delivered to a target tissue proximate to the nerve, the treatment cycle may comprise a cooling phase wherein cooling fluid flows into the lumen so that liquid from the cooling fluid flow vaporizes within the lumen to provide cooling to the nerve so as to treat spasticity.

The present invention generally relates to improved medical devices, systems, and methods. In many embodiments, devices, systems, and methods for locating and treating a target nerve with cold therapy are provided. For example, a focused cold therapy treatment device may be provided that is adapted to couple with or be fully integrated with a nerve stimulation device such that nerve stimulation and focused cold therapy may be performed concurrently with the cryo-stimulation device. Improvements in nerve localization and targeting may increase treatment accuracy and physician confidence in needle placement during treatment. In turn, such improvements may decrease overall treatment times, the number of repeat treatments, and the re-treatment rate. Further, additional improvements in nerve localization and targeting may reduce the number of applied treatment cycles and may also reduce the number of cartridge changes (when replaceable refrigerant cartridges are used).

Methods, devices, and systems employ cryolysis of oropharyngeal adipose tissues to selectively remove fat cells from the tissues causing obstructive sleep apnea. In various embodiments, a chilled liquid—e.g., a liquid or air—is applied to the target tissue at a temperature and for a duration sufficient to cause cryolysis.

Disclosed are a fast planning system and method applicable to ablation therapy. The system comprises an input device, a calculation device and an output device, the calculation device obtains a boundary of the tumor and an actual position of an ablation probe relative to a tumor through the input device, the quantitative relationship between the ablation range and the ablation parameters of the ablation probe, and maximum ablation range parameters of the ablation probe. The system obtains the ablation parameters of the ablation probe by means of the calculation device based on the obtained information, outputs the ablation parameters by means of the output device, and obtains a revised planning suggestion. The present invention resolves the issue of incomplete ablation in a clinical ablation operation possibly resulting from deviation of an actual probe insertion position from a probe insertion position planned prior to the operation, and is conducive to achieving precision control over thermal dosage at a focal region and ensuring the effectiveness of ablation therapy.

There is provided herein an assemblable cryoneedle for performing a cryo-treatment, particularly but not limited to, for cryo-treatment of keloids and scars. According to some embodiments, the assemblable cryoneedle includes an outer elongated needle having a sealed distal portion, an inner elongated needle, and a connector, configured to connect and allow fluid communication therebetween. The inner elongated needle is configured to be inserted into the outer elongated needle, forming a double lumen configuration. The outer elongated needle is configured to be inserted into a treatment area of a subject.

A cryogenic system as well as a method of generating a pressurized, sub-cooled mixed-phase cryogen and a method of delivering such a cryogen to a cryoprobe are disclosed. In an embodiment, the cryogenic system includes a reservoir containing a liquid cryogen and a sub-cooling coil immersed in the liquid cryogen. The cryogen is supplied to the sub-cooling coil and is cooled under pressure to produce a pressurized mixed phase cryogen within the sub-cooling coil. This pressurized mixed phase cryogen is provided via supply line to a cryo-device for use.

Device, systems, and methods for cryoablation are described herein. In some implementations, the devices and systems are used to for cryoneurolysis or cryoablation of nerves. An example cryoablation probe includes a tubular member having a proximal end and a distal end. The tubular member has a probe tip arranged at the distal end. The probe also includes one or more energy elements arranged along an axial direction of the tubular member, and one or more sensor elements arranged along the axial direction of the tubular member.

Devices, systems and methods are provided for treating conditions of the reproductive tract. A number of conditions can afflict the lining and cell layers deeper within the anatomical structures. For example, cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is a condition involving abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer in situ (CIS). Other conditions include human papillomavirus (HPV)-related cervical disease, various endometrial diseases, acute and chronic cervicitis, and various infections (e.g. trichomoniasis) to name a few. In some embodiments, treatments eliminate diseased, damaged, abnormal or otherwise undesired cells leaving the tissue framework intact. This allows the tissue to regenerate in a normal fashion, avoiding the formation of scar tissue. When the tissue framework is left intact, the framework structure repopulates with healthy cells, regenerating the normal tissue without altering the structural properties.