Embodiments include a cryogenic device for alleviating pain by cryogenically treating a nerve, the cryogenic device including a handpiece; a needle coupled to a distal end of the handpiece, the needle including a needle lumen, the needle being configured for insertion into a skin of a patient along an insertion axis at a site laterally displaced from a treatment zone proximate to the nerve. The needle is configured to resiliently bend after insertion away from the insertion axis, such that at least a portion of the needle is adapted to traverse a skin layer laterally toward the treatment zone. The device includes a cooling fluid supply tube extending distally into the needle lumen; and a cooling fluid source, wherein the cooling fluid source is coupled to the cooling fluid supply tube to direct cooling fluid into the needle lumen.

A medical guidance apparatus (100) includes a base assembly (110) configured to be attached to a subject and a guide (150) configured to be removably mated with the base assembly (110). The base assembly (110) has an opening (160), and the guide (150) includes a rotatable ring (152) and an arc member (154). The arc member (154) includes a first end (162) and a second end (164), the first end of the arc member is connected to the rotatable ring (152) and the second end extends diametrically opposite to the first end across the rotatable ring. A probe holder (600) is mounted on the arc member (154) so as to hold a needle-like instrument (2161) at a desired angle relative to an axis (Ax) of the rotatable ring (152). In some embodiments, the arc member is monolithically integrated with the rotatable ring. In other embodiments, the arc member is pivotable and/or completely removable from the rotating ring.

Systems and methods for tumor ablation with controlled precision of a temperature profile utilizing a tumor ablation probe device may include disposing a distal end of the tumor ablation probe device in a tissue, the distal end including a plurality of electrothermal modules (ETMs) on probe arm(s), each ETM including a first surface component electrically connected to a second surface component; supplying a first voltage of a first polarity or a second voltage of a second polarity to at least one ETM, and repeatedly alternating between the first polarity and the second polarity based on a time sequence cycle. When the first polarity is supplied, the ETM heats the first surface component and cools the second surface component, and when the second polarity is supplied, the ETM cools the first surface component and heats the second surface component. Each ETM and/or probe arm is configured for independent control.

A system and method are presented for treating targeted tissue using cryoablation. An introducer canula and a cryoprobe are inserted the targeted tissue. The cryoprobe is cooled and an ice ball is formed. The cryoprobe is removed while the ice ball is still frozen, and an ultrasound catheter is inserted. Ultrasound generated within the ice ball is used to determine the distance from the ultrasound catheter to a perimeter of the ice ball. This is repeated at different angles to model a slice of the ice ball. The ultrasound catheter is moved radially, and the process is repeated to create a model of at least a portion of the ice ball. The ice ball model can be displayed on a registered set of images representing the targeted tissue to ensure that the tissue lies within the treatment zone of the ice ball.

A method for providing thermal conductivity data relating to an anatomical structure, comprises: receiving first spectral computed tomography data relating to the anatomical structure; calculating a fat map of the anatomical structure and a water map of the anatomical structure based on the first spectral computed tomography data; calculating the thermal conductivity data relating to the anatomical structure based on the fat map and the water map; and providing the thermal conductivity data.

Disclosed herein are devices, systems, and method for multi-stage, reusable coupling. Such a coupler can have a formable flow path and can include a first sealing engagement and a second sealing engagement. The first sealing engagement can be configured to provide a first seal of the coupler at a first temperature condition. The second sealing engagement can be configured to provide a second seal of the coupler at a second temperature condition that is different from the first temperature condition.

A tumor targeting ablation planning device and method include providing a predetermined ablation profile and a segmented tumor to be treated in an ablation procedure. A contour of the segmented tumor is generated and the predetermined ablation profile is overlapped with a part of the segmented tumor to form an overlapping region, which is identified. Further, a predetermined safety factor is applied to at least a part of the at least one segmented tumor in the overlapping region to generate a modified overlapping region. Parts of the overlapping region that are arranged outside the modified overlapping region are determined as overlapping portions. A display is configured to: display the contour of the segmented tumor, display the predetermined ablation profile overlapped with the at least part of the segmented tumor in the overlapping region, and display the overlapping portions in relation with the contour and the ablation profile as virtual planning ablation result.

A magnetic resonance imaging (MRI) guided surgical system is provided that includes one or more surgical tools having components configured to develop reactive effects when exposed to MR signals generated by the MRI system. The system includes a control system that can determine whether the MR system is generating MR signals, and if the control system determines that the MR system is generating MR signals, mitigates the reactive effects of MR signals on components of the surgical tools. The system can include a cryoablation system with a cryoprobe having a probe shaft being made of a metallic material. If the control system determines that the MR system is generating MR signals, the control system can electrically disconnect the cryoprobe and/or ignore electrical signals generated by the electric heater in response to exposure to MR signals, and/or initiate a cooling operation of the probe shaft, whereby the cooling operation.

An apparatus for performing cryosurgery, especially suited for the sacroiliac joint. The apparatus includes a first expansion tube having a first length; a second expansion tube having a second length, wherein the second length is longer than the first length; a first supply tube supplying a cooling agent to the first expansion tube; a second supply tube supplying another cooling agent to the second expansion tube; and a drain tube for removing cooling agents from an enclosed working part, wherein the first expansion tube supplies the cooling agent to a first portion of the working part, the second expansion tube supplies the another cooling agent to a second portion of the working part, the working part further including a tip; wherein the first expansion tube and the second expansion tube are positioned inside a casing.

Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated.