The present application describes a substituted aryl compound used as an RAD51 inhibitor and a pharmaceutically acceptable salt thereof. The compound has the structure as represented by Formula (I) and has the substituents and structural features as described in the present application. Furthermore, the present application describes a pharmaceutical composition containing the compound as represented by Formula (I) or the pharmaceutically acceptable salt thereof, and the use of the compound as represented by Formula (I) or the pharmaceutically acceptable salt thereof and the pharmaceutical composition containing same in the preparation of a drug for preventing or treating RAD51 mediated diseases.

##STR00001##

Provided are a compound and an organic electro-optical device containing the same. The compound has a structure represented by Formula I. The organic electro-optical device comprises an anode, a cathode, and at least one organic thin film layer located between the cathode and the anode. The molecule of the compound provided by the present disclosure has higher rigidity, a large conjugated system, a deeper LUMO energy level, a higher triplet energy level and good molecular stability, and is not easy to crystallize, and thus the compound can be used as an electron transport material or a hole blocking material of the organic electro-optical device, facilitating the reduction of the turn-on voltage of the device, the improvement of current efficiency and the increase of service life.

An object of a first aspect of the present invention is to provide a radical generating catalyst that can generate (produce) radicals under mild conditions. In order to achieve the above object, a first radical generating catalyst according to the first aspect of the present invention is characterized in that it includes ammonium and/or a salt thereof. A second radical generating catalyst according to the first aspect of the present invention is characterized in that it includes an organic compound having Lewis acidic properties and/or Brønsted acidic properties.

The present specification relates to a heterocyclic compound represented by Chemical Formula 1, and an organic light emitting device comprising the same.

Fluorinated photoinitiators and polymerizable compositions including such fluorinated photoinitiators and at least one free-radically polymerizable monomer, oligomer, or mixture thereof. Multilayer films including a substrate and at least a first layer overlaying a surface of the substrate also are described, in which the at least first layer includes a (co)polymer obtained by polymerizing the foregoing polymerizable compositions. Processes for making a multilayer film using the polymerizable composition also are taught. Articles including the multilayer film also are disclosed, in which the article preferably is selected from a photovoltaic device, a display evice, a solid-state lighting device, a sensor, a medical or biological diagnostic device, an electrochromic device, light control device, or a combination thereof.

Epidermal growth factor receptor (EGFR) inhibitors are provided. In particular, 4-substituted-2-(N-(5-substituted allyl amide)phenyl)amino)pyrimidine derivatives of formula (I), a preparation method and use thereof as an EGFR inhibitor are provided. The 4-substituted-2-(N-(5-substituted allyl amide)phenyl)amino)pyrimidine derivatives of formula (I) have inhibitory activity against the L858R EGFR mutant, the T790M EGFR mutant and the exon 19 deletion activating mutant, and can be used to treat diseases mediated alone or in part by EGFR mutant activity. The derivatives of formula (I) can be used to treat and/or prevent cancers, particularly non-small cell lung cancer.

##STR00001##

A photoinitiator mixture comprising the components (a) a compound of the formula (I) ##STR00001##
wherein Ar.sub.1 and Ar.sub.2 independently of each other are ##STR00002##  or naphthyl which is unsubstituted or substituted one or more times by R.sub.1, R.sub.2, R.sub.3 or R′; R.sub.1 and R.sub.3 in-dependently of each other are C.sub.1-C.sub.4alkyl, C.sub.1-C.sub.4alkoxy or halogen; R.sub.2 is hydrogen, C.sub.1-C.sub.4alkyl, halogen, C.sub.1-C.sub.4alkoxy or C.sub.2-C.sub.20alkoxy which is interrupted by one or more O; Q is C.sub.1-C.sub.4alkylene; R.sub.4 is methyl or ethyl; R′ and R″ independently of each other are hydrogen or PG-Y—R′″—X—; PG is a polymerizable group or methyl or ethyl; Y is a direct bond, O or S; X is a direct bond, O or S; R′″ is a direct bond, C.sub.1-C.sub.20alkylene or C.sub.2-C.sub.20alkylene which is interrupted by one or more O; (b) one or more compounds of the formula (II) ##STR00003##
wherein Ar.sub.1, Ar.sub.2 and Q are as defined above, and R.sub.5 is for example C.sub.3-C.sub.30alkyl which is unsubstituted or substituted and (c) optionally a compound of the formula (III)
R.sub.5—OH  (III),
wherein R.sub.5 is as defined above; provides a liquid photointiator.

A nanocrystal capable of light emission includes a nanoparticle having photoluminescence having quantum yields of greater than 30%.

Certain phosphonic acid salts heated at temperatures over 200° C. generate thermally stable, highly efficient flame retardant materials well suited for use as flame retardant additives in polymers. The flame retardants of the invention can be used as the sole flame retardant in a composition or in combination with other flame retardants, synergists or adjuvants.

The invention relates to alkenyl(perfluoroalkyl)phosphinic acids, to the preparation and intermediates thereof, to the use thereof as monomers for the preparation of oligomers and/or polymers, to the corresponding oligomers/polymers, to the corresponding support materials comprising the oligomers/polymers, and to the use thereof as ion exchangers, as catalysts or extraction medium and corresponding salts thereof.