Patent classifications
C
CHEMISTRY; METALLURGY
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C07
ORGANIC CHEMISTRY
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C07F
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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9/00
Compounds containing elements of Groups 5 or 15 of the Periodic Table
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C07F9/54
Quaternary phosphonium compounds
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C07F9/5435
Cycloaliphatic phosphonium compounds
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C07F9/5435

Mitochondria-targeted atovagone: a more potent and more effective antitumor, antimicrobial, and antimalarial drug
12594283 · 2026-04-07 · ·

The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.