A heating blade unit, a treatment tool, and a method of manufacturing a heating blade unit are disclosed. The heating blade unit includes: an electric heater, a blade, and a cover made of a thermosetting resin. The blade includes a treatment surface, an installation surface that is provided on a side opposite to the treatment surface and on which the electric heater is installed, and a support surface that is provided at a position different from a position at which the installation surface is provided. The cover integrally covers the electric heater, and one or more surfaces of the blade.

A catheter and tissue cutting system percutaneously permits the creation of an anastomosis between a first and second anatomical structure, such as a vein and an artery. The system comprises a catheter having a main body with a lumen and tapered distal tip, configured to be moved distally into the first anatomical structure over a primary guidewire. A cutting electrode is nested in the main body, with a lumen which tracks over a secondary guidewire, and is insertable into the secondary anatomical structure. An energy supply is operative to energize the cutting electrode in order to cut a tissue wall defining the first anatomical structure.

An ablation catheter system includes: a catheter shaft; a balloon attached to the catheter shaft; a lumen extending through the catheter shaft in a longitudinal direction thereof and communicating with the interior of the balloon; a heating electrode and a temperature sensor provided in the interior of the balloon; a heater that applies electrical energy to the heating electrode; a pressure sensor; a balloon volume sensor; and a processor that calculates the estimated depth of ablation, using as variables, heating temperature of a generator, ablation time of the generator, a value of balloon pressure obtained from the pressure sensor and a value of balloon volume obtained from the balloon volume sensor.

Provided herein are expandable devices, rail systems, and motorized devices, in one embodiment, an expandable device comprises an expandable sac having a tool housed therein. The expandable device is optionally configured for operation while inside a body cavity. The expandable device optionally comprises at least one rail in the sac, and at least one railed device coupled to the rail for movement there on. Movement of the railed device on the rail is provided by, for example, a motor such as an electromagnetic motor or an inch-worm type motor. Expandable devices can be used, for example, to perform minimally invasive medical procedures requiring access to a body cavity. Expandable devices can also be used, for example, to provide safe and stable transport of instruments to the body cavity.

Residual, refractory or relapsed cancer is treated by immunostimulation in the presence of allogeneic immune effector cells, optimally in combination with radiation therapy. The methods of the disclosure induce a systemic allogeneic anti-tumor immune response that results in tumor regression in untreated sites of disease, i.e. non-injected, non-irradiated, etc.

A computer-implemented method includes accessing an activation state of an energy-based surgical instrument, accessing at least one image of tissue, accessing control parameter values of a generator configured to provide energy to the energy-based surgical instrument, storing the control parameter values, receiving input information, annotating the stored control parameter values and the at least one image based on the received information, and tagging the annotated control parameter values and the annotated at least one image.

A method of creating an anastomosis includes steps of advancing a distal tip of a catheter device through a first blood vessel into a second blood vessel, while simultaneously advancing a proximal base of the device into the first vessel, contacting a wall of the first vessel with a distal blunt surface on the proximal base. A further step is to retract the distal tip so that a proximal blunt base of the distal tip contacts a wall of the second vessel, thereby capturing the two vessel walls between the blunt surfaces of the proximal base and the distal tip. A controlled pressure is applied between the two blunt surfaces to compress and stabilize the captured tissue and approximate the vessel walls. A clip is deployed through the captured tissue to hold the tissue in place during the anastomosis procedure. The anastomosis is created by applying cutting energy to the captured tissue.

An end effector structure for tissue ablation powered by microwave energy source and end effector including a microwave antenna surrounded by a segments from microwave absorbing materials. Microwave absorbing material is a material, transparent to microwave energy impregnated with microwave absorbing particles, and has differing microwave transmission and/or absorption characteristics at different locations along the microwave antenna to apply to the desired bi-tissue, a selective amount of microwave and/or heat energy. Microwave transparent material can be ceramic, silicone, fluorosilicone, fluorocarbon, thermoplastic rubber, ethyline propylene diene monomer, urethane etc. Microwave absorbing particles can be from nickel (Ni), copper (Cu), Aluminum (Al), Ag/Cu; Ag/Al; Ag/Ni; Ag/Glass, nickel-plated graphite, silver-plated aluminum, silver-plated copper, silver-plated nickel, silver-plated glass and pure silver etc.

A system and method for supporting multi-probe guidance are disclosed. The system comprises: a medical guidance apparatus comprising: a rotatable portion which is rotatable around a first axis; an arc guide attached to or integrally formed with the rotatable portion, and a probe holder movably mounted on the arc guide. The probe holder is rotatable around a second axis perpendicular to the first axis by being translated along an arcuate path defined by the shape of the arc guide. In one embodiment, the probe holder includes a plurality of probe channels to guide a corresponding plurality of probes parallel to each other towards a subject. In other embodiment, the probe holder includes a single probe channel which is offset from a center point of the guidance apparatus by a fixed distance such that each probe can be inserted sequentially through a different insertion point without colliding at the center point.

A surgical instrument for use with a robotic surgical system includes a knife blade configured to cut tissue and a knife tube coupled to the knife blade and configured to translate to move the knife blade for cutting tissue. The surgical instrument also includes a gearbox assembly coupleable to a robotic surgical system and configured to translate the knife tube to move the knife blade for cutting tissue and a knife blade lock operably coupled to the gearbox assembly. The knife blade lock is movable from a locked position wherein the knife blade lock prevents translation of the knife tube to an unlocked position in response to coupling of the gearbox assembly to the robotic surgical system wherein the knife tube is permitted to translate to move the knife blade for cutting tissue.