A combined isolator-diplexer device for supplying radiofrequency (RF) energy and microwave energy obtained from separate sources to a probe via a common signal pathway. The invention combines into a single unit all the necessary components to isolate a microwave channel from an RF channel whilst providing a high withstanding voltage (e.g. greater than 10 kV). The device comprises a waveguide isolator for isolating the microwave channel having a pair of DC isolation barriers arranged therein to provide a pair of series-connected capacitive structures between a ground conductor at an output of the combining circuit and a conductive input section of the waveguide isolator.

An electrosurgical apparatus for treating fluid-filled biological growths by replacing the fluid within the growth with a substance that assists in delivering treatment energy.

The treatment energy may be microwave energy or may be thermal energy derived from microwave energy. The apparatus comprises an instrument having a radiating tip portion, and a fluid delivery mechanism for transporting fluid to and from a treatment zone located around the radiating tip portion. The fluid delivery mechanism comprises a rigid insertion element arranged to extend into the treatment zone, whereby fluid can be aspirated from the treatment zone, and a substance injected into the treatment zone to replace the aspirated fluid. The injected substance has dielectric properties selected to facilitate uniform delivery of treatment energy to biological tissue in the treatment zone.

A device and method of using the device to detect the presence and composition of clots and other target objects in a circulatory vessel of a living subject is described. In particular, devices and methods of detecting the presence and composition of clots and other target objects in a circulatory vessel of a living subject using in vivo photoacoustic flow cytometry techniques is described.

An electrosurgical system including or connected to an output circuitry comprising an electrosurgical device and an electrical cable is modelled during a cable interrogation phase using a transfer matrix in order to determine a leakage capacitance in the electrosurgical system. After the leakage capacitance is assigned or set to a virtual capacitor in the transfer matrix, an output parameter of the electrosurgical system, such as output voltage, output current, output impedance or output electrical power, may be determined by applying an actual input voltage to the output circuitry and measuring a resulting input current, and multiplying the input voltage and measured current by the transfer matrix.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.

In general, devices, systems, and methods for multi-source imaging are provided.

A quantum cardiac electrophysiology device comprising an array of consumable half-ferromagnetic active electrodes connected to an array of semiconductor of half-ferromagnetic selector switches over an array of half-ferromagnetic resistors to a neutral charges out of the heart, by casting and/or inking the arrhythmic substrate of an arrhythmia by the electrophysiology quantum entan- glement of said arrhythmic substrate.

The invention provides a tip that permits therapeutic electromagnetic energy systems to deliver multiple beams of overlapping, partially overlapping, and non-overlapping electromagnetic energy in the treatment of tissue disorders and conditions. The tip finds use with laser systems, intense pulsed light systems, LED systems, radiofrequency systems, and microwave systems.

A quantum spin liquid (QSL) electrophysiology device comprising a spontaneous and an induced quantum arrhythmia vacuum states, switchable between them through at least one entangled measurement of one negative differential resistance.

Disclosed herein are devices, systems, and methods for use in a magnetic resonance imaging (MRI)-guided procedure in which focused energy is applied to an area of interest of a subject. Disclosed herein are coupling baths comprising an aqueous solution comprising a plurality of paramagnetic particles dispersed in water, wherein, when magnetic resonance images are collected from the area of interest of the subject for MRI guidance: the coupling bath is located proximate to the area of interest, and the composition, the average particle size, the shape, the concentration, the presence or absence of the capping layer, the identity of the plurality of ligands when the capping layer is present, the average thickness of the capping layer when the capping layer is present, or a combination thereof is/are selected such that the coupling bath reduces or prevents imaging artifacts in the magnetic resonance images for the MRI guidance.