The present invention relates to a method for obtaining chitin and/or chitosan from insect cuticles. More particularly, the method according to the present invention comprises a first enzymatic hydrolysis of insect cuticles using at least one endopeptidase, separation from the hydrolysis medium of the hydrolyzed cuticles resulting from the first enzymatic hydrolysis, and a second enzymatic hydrolysis of the hydrolyzed cuticles using at least one endopeptidase, excluding exopeptidase.

A preparation method of a hydrogel of a mercapto-modified macromolecular compound includes the steps of combining the mercapto-modified macromolecular compound with an acrylated macromolecular compound and/or an acrylated micromolecular crosslinker. The mercapto-modified macromolecular compound can be crosslinked with the acrylated macromolecular compound and/or the acrylated micromolecular crosslinker under physiological conditions to form the hydrogel. Due to the rapid mercapto-vinyl crosslinking reaction, the formed hydrogel system can be quickly gelled in situ after being injected into the body. The hydrogel is thus suitable for use in the fields of biomedicine, medical cosmetic plastic surgery and cosmetics.

The present invention relates to an acetylated amphiphilic carbohydrate compound of average molecular weight 1-50 kDa which is based on a glycol chitosan, wherein the levels of acetylation can be modified. The compound can be formulated with hydrophobic compounds such as drugs. The degree of acetylation of the carbohydrate compound is optimised to maximise solubilisation of the drugs. The compound is formulated with drugs and is useful in therapy.

An oil repellent agent including a modified natural product having at least one hydroxyl group, wherein a hydrogen atom of the hydroxyl group is replaced with an R group represented by —Y—Z, wherein Y represents a direct bond, —C(═O)—, —C(═O)—NR′— or —C(═S)—NR′—, where R′ represents a hydrogen atom or a C.sub.1 to C.sub.4 alkyl group); and Z represents a hydrocarbon group having 1 to 40 carbon atoms and optionally having a substituent or a polysiloxane. The natural material is a natural product other than starch and preferably is a monosaccharide, a polysaccharide, glycerin or polyglycerin. Also disclosed is a textile product to which the oil-resistant agent is attached, an oil-resistant paper and a method of treating paper with the oil-resistant agent.

Large molecular weight alginates which are covalently modified to store and release nitric oxide, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates may be tailored to release nitric oxide in a controlled manner and are useful for eradication of both planktonic and biofilm-based bacteria.

The present application belongs to the field of life health, and discloses a sugar chain and a composition thereof, and use in the prevention and/or treatment of coronavirus infection. The sugar chain contains any one or more of Neu5Acα2-N.sub.1Gal building blocks, and/or any one or more of xFuc-N.sub.1Gal-N.sub.1(xFuc-N.sub.1)GlcNAc building blocks, at the non-reducing end, where, x=0 or 1, and N.sub.1=1, 2, 3, 4 or 6. A glycosidic bond formed between Neu5Ac and Gal is an α2 glycosidic bond. In the xFuc-N.sub.1Gal-N.sub.1(xFuc-N.sub.1)GlcNAc building blocks, a glycosidic bond formed between any two adjacent monosaccharides is an α1 or β1 glycosidic bond. The specific building block contained at the non-reducing end of the sugar chain blocks the binding of the virus to the host, thereby blocking virus invasion and infection of the respiratory tract/lung, and achieving the specific prevention and treatment.

A water-soluble and/or water-swellable hybrid polymer comprising: (i) from 5 wt.-% to 95 wt.-% water-soluble and/or water-swellable polysaccharide polymer selected from the group consisting of xanthan gum, carrageenan, guar gum, chitosan, alginate and combinations thereof; (ii) from 5 wt.-% to 95 wt.-% synthetic polymer comprising up to 100 mol-% repeating units according to Formula (1a): ##STR00001##
wherein components (i) and (ii) are polymerized by radical precipitation polymerization in a polar solvent.

A method for manufacturing a compound comprising at least one imine group, the method comprising a step of reaction between a first compound comprising at least one amine group and a second compound comprising at least one carbonyl group, the reaction step being carried out in the presence of at least one supercritical fluid.

The present disclosure relates to redox active materials, such as the compound of formula (I), comprising at least one 2,5-dithio-7-azabicyclo(2.2.1)heptane unit connected to a surface thereof, as well as processes for making said redox active materials. The present disclosure relates to a method for recovering a metal, comprising reacting a metal in oxidized state with said redox active material. The present disclosure relates to uses of these redox active materials in sensors, electronic materials and for extracting metals.

The present invention relates to a process for producing a low endotoxin alkali chitosan, chitin, chitosan derivative or chitin derivative, and also to a process for producing low endotoxin neutral chitosan, chitosan salt and chitosan derivatives, and to the products of such processes. The process comprises contacting chitosan, chitin, chitosan derivative or chitin derivative with an alkali solution having a concentration of less than 0.25M to form a mixture; leaving the mixture for a period of less than 12 hours and optionally drying the mixture. The low endotoxin alkali chitosan may be used in the manufacture of other useful chitosan based products.