The presently-disclosed subject matter includes hydrophilic thioketal polymers and scaffolds formed therefrom.

The presently-disclosed subject matter includes hydrophilic thioketal polymers and scaffolds formed therefrom.

Embodiments of the disclosure generally provide compositions and methods related to oligomeric and polymeric urethane materials that contain hydrolyzable polythioaminal groups for use in biomedical applications.

A thiol group-containing polymer represented by:
HS(RS.sub.r).sub.nRSH
wherein R is an organic group including a OCH.sub.2O bond and a branched alkylene group, n is an integer of from 1 to 200, r is an integer of from 1 to 5, an average value of r is 1.1 or more and lower than 1.8, and the thiol group-containing polymer is a liquid at room temperature and has a specific gravity at 23 C. of 1.20 to 1.27.

A thiol group-containing polymer represented by:
HS(RS.sub.r).sub.nRSH
wherein R is an organic group including a OCH.sub.2O bond and a branched alkylene group, n is an integer of from 1 to 200, r is an integer of from 1 to 5, an average value of r is 1.1 or more and lower than 1.8, and the thiol group-containing polymer is a liquid at room temperature and has a specific gravity at 23 C. of 1.20 to 1.27.

The invention relates to new, water-emulsifiable isocyanates, to a process for preparing water-emulsifiable isocyanates, and to the use thereof.

The invention relates to new, water-emulsifiable isocyanates, to a process for preparing water-emulsifiable isocyanates, and to the use thereof.

A method of producing a thiol group-containing polymer includes reacting bis(2-chloroethyl) formal with sodium hydrosulfide, wherein the thiol group-containing polymer is represented by general formula:
HS(RS.sub.r).sub.nRSH
where R is an organic group including a C.sub.2H.sub.4OCH.sub.2OC.sub.2H.sub.4 structure, n is an integer of from 1 to 200, r is an integer of from 1 to 5, and the average value of r is 1.1 or more and lower than 1.8, and wherein the thiol group-containing polymer is a liquid polymer.

A method of producing a thiol group-containing polymer includes reacting bis(2-chloroethyl) formal with sodium hydrosulfide, wherein the thiol group-containing polymer is represented by general formula:
HS(RS.sub.r).sub.nRSH
where R is an organic group including a C.sub.2H.sub.4OCH.sub.2OC.sub.2H.sub.4 structure, n is an integer of from 1 to 200, r is an integer of from 1 to 5, and the average value of r is 1.1 or more and lower than 1.8, and wherein the thiol group-containing polymer is a liquid polymer.

A thiol group-containing polymer represented by:

HS(RS.sub.r).sub.nRSH

wherein R is an organic group including a OCH.sub.2O bond and a branched alkylene group, n is an integer of from 1 to 200, r is an integer of from 1 to 5, an average value of r is 1.1 or more and lower than 1.8, and the thiol group-containing polymer is a liquid at room temperature and has a specific gravity at 23 C. of 1.20 to 1.27.