Systems, methods, and devices are provided for assisting or performing guided interventional procedures using custom templates. The system uses pre-procedure scans of a patient's anatomy to identify targets and critical structures. A template is then manufactured containing guide elements. During a procedure, the template may be aligned to the patient and instruments passed though the guide elements and into various targets. The template may be aligned using one or more of, for example, a position sensing system or a live imaging modality to register the patient to the template. The system makes optional use of devices designed to immobilize or track an organ during therapy.

An apparatus for targeting an injection site using anatomical landmarks includes a first landmark identifier, a second landmark identifier, and a targeting band. The targeting band is connected with the first landmark identifier at a first end and a second landmark identifier at a second end. At least a portion of the targeting band is linearly deformable. In another embodiment, an apparatus for targeting an injection site using anatomical landmarks on a patient includes a targeting band having a first end and a second end, at least a portion of the targeting being linearly deformable, a first landmark identifier pivotably connected to the targeting band at the first end, a second landmark identifier configured to be connected with the second end of the targeting band; and a fastener configured to secure the first and second landmark identifiers to the patient.

A method is disclosed of making a customized intraoral positioning device to be positioned within a patient's mouth for radiation therapy planning and treatment of a head and/or neck of the patient.

A stereotactic device for primate brains indicates a brain coordinate reference point of a primate using a simulator for indicating a brain coordinate reference point, thereby providing an initial setting to a zero point corresponding to the brain coordinate reference point. The brain coordinate reference point is conveniently and accurately indicated without relatively expensive equipment, such as a magnetic resonance imaging (MRI) scanner, to determine brain coordinates of the primate, so that a targeting procedure can be conducted on the brain.

An apparatus for providing at least one treatment to at least one tissue having a first structural arrangement configured to expand a first portion at a distal end of the apparatus, a second structural arrangement configured to expand a second portion at the distal end and at least one lumen associated with at least one of the first structural arrangement and/or the second structural arrangement. The first structural arrangement and/or the second structural arrangement can be configured to position the at least one lumen at a particular position with respect to the tissue. A tip is configured to aid in the insertion of the apparatus into the tissue(s).

A surgical device for automated drilling includes a drill comprising a drill bit configured to bore through bone and a detector comprising a tissue detection sensor. The drill and detector are independently actuable for insertion and removal of the drill bit and the tissue detection sensor in a bore generated by the drill bit. A surgical system can include the surgical device and a controller configured to actuate the drill to bore through bone, actuate the drill to retract the drill bit from the bore, actuate the detector to insert the tissue detection sensor into the bore, and determine a tissue characteristic at a distal location of the bore based on a sensed signal from the tissue detection sensor.

A head immobilization system for immobilizing a patient's head in a supine position of the patient includes a support rail structure adapted to be coupled to a patient rest. The system can further include a mask frame adapted to be coupled to at least one deformable upper mask sheet. The mask frame is releasably connected to the support rail structure via a first interface section and a second interface section, with at least two pins protruding from the first interface section in a first direction, and at least two pin-receptions provided at the second interface section. Each one of the pin-receptions receives one of the pins. A catch-mechanism for each pin-reception and each corresponding pin allows the pin to be pushed further into the pin-reception in the first direction, but interlocks in case of an attempted withdrawal of the pin from the pin-reception in a second, opposite direction.

An intraoral positioning device (IPD) is disclosed. The IPD is to be positioned within a patient's mouth for intensity-modulated radiation therapy (IMRT) planning and treatment. The intraoral positioning device comprises: a bite stent having upper and lower sections, the upper section configured to engage an upper oral structure of the patient's mouth and the lower structure configured to engage a lower oral structure of the patient's mouth during IMRT planning and treatment; a tongue displacement stent extending from and fixed to the bite stent, the tongue displacement stent configured to displace the tongue of the patient in a direction with respect to a base of the patient's mouth in accordance with a patient's prescription for IMRT planning and treatment, whereby the patient's tongue is positioned in a motionless state during the IMRT planning and treatment; and a deployment handle extending from and fixed to the bite stent.

A skull clamp for patient stabilization comprises a pair of arms where the arms include upright portions and lateral portions. The upright portions and lateral portions define longitudinal axes, where the intersection of these axes defines an arm angle that is greater than about 90 degrees. In some instances the arm angle is between about 100 and about 120 degrees. In some instances the arm angle is about 110 degrees. The skull clamp can have rails integrated in the arms for attaching various accessories to the skull clamp.

A jig for placing a screw to stabilize a femoral nail comprises a shell, a drill guide assembly movably mounted on the shell, and having a plurality of radiopaque markers affixed thereon, a magnetic field generator, and a plurality of magnetic location sensors responsive to magnetic fields produced by the magnetic field generator. A position processor is operative to compute positional information of the magnetic location sensors based on signals communicated thereto. The positional information is placed in registration with an anatomical image so that the drill guide assembly can be aligned with a transverse bore in the femoral nail.