The present disclosure generally provides methods of implanting an implantable device in contact with a brain of a subject. Also provided are kits and systems for the implantation of one or more implantable devices.

A surgical robot system includes a surgical robot, a robot arm connected to such surgical robot, and an end-effector connected to the robot arm. A registration fixture is used in conjunction with various registration systems in the surgical robot system. Such registration systems likewise include a detachable base in the form of a detachable dynamic reference base, along with an associated mount, the dynamic reference base and mount having certain features which permit the dynamic reference base to be selectively attached, detached, and reattached at different phases of an operation, whether pre-operative or intra-operative, and such successive attachments are done without the dynamic reference base, and tracking markers associated therewith, losing registration. Related methods allow for the more efficient and effective performance of operations by virtue of the dynamic reference base maintaining its registration during attachments and reattachments.

An intracortical-detection device including: at least one electrode that contacts a group of neurons; a first body, forming a surface that contacts a portion of a cerebral region; a first motor that moves the electrode with respect to the first body; a second motor; and a second body, operatively connected to the second motor, the first and second bodies being able to slide with respect to one another in a first direction, under the action of the second motor. The detection device moreover includes a sensor generating an electrical signal indicating a pressure exerted by the portion of cerebral region on the surface.

Some embodiments of the present disclosure comprise improved systems and methods for monitoring physiological parameters such as intracranial pressure (“ICP”), intracranial temperature, and subject head position. For example, in some embodiments, an implantable apparatus for measuring ICP can be implanted into a subject skull. The apparatus can comprise an implant body having a hermetically sealed chamber housing a gas at a reference pressure, and a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and includes a plurality of ports. A barrier can cover the ports of the distal end of the pressure conduction catheter, wherein the barrier and pressure conduction catheter are filled with a number of gas molecules so that the barrier is not in tension in a predefined range of ICPs.

A transcranial fastening device (1) for a drainage catheter (3), comprising an external body (5) being equipped with a passage (P), the passage (P) being equipped with blocking means (9) of the drainage catheter (3) adapted to allow a sliding of the drainage catheter (3) through the passage (P) along a first movement direction (M1) and to prevent a sliding of the drainage catheter (3) through the passage (P) along a second movement direction (M2).

An anchoring system for cannulas or tools to be inserted into a surgical workspace in the body, particularly the brain, of a patient. The system comprises a mounting ring which may be fixed to the skull to both secure the system to the skull and protect the skull opening from passage of cannulas and tools, a resilient clip with grasping jaws adapted to firmly grasp a cannula or tool, and a flexible membrane secured to the outer rim of the mounting ring and the clip.

The present invention relates to methods of removing a lesion from a patient. A method of removing a lesion from a patient includes positioning wire loops of a probe device relative to the lesion. The wire loops are simultaneously rotated and expanded to cut material from the lesion. Irrigation fluid is supplied, via the probe device, to irrigate the material cut from the lesion. The supplied irrigation fluid is aspirated, via the probe device, to facilitate removal of the material cut from the lesion.

Methods, devices, and systems induce neuromodulation by focusing a source of stimulation through a skull/brain interface in the form of an aperture formed in the skull, a naturally occurring fenestration in the skull, or a transcranial channel. Methods, devices, and systems identify where to locate skull/brain interfaces, accessories that can be used with the interfaces, and features for controlling stimulation delivered through the interfaces. Multiple indications for the skull/brain interfaces include diagnosis and treatment of neurological disorders and conditions such as epilepsy, movement disorders, depression, Alzheimer's disease, autism, coma, and pain.

Trajectory frame assemblies for image guided surgical systems have a trajectory frame with a support column that can removably secure different components such as a tracking probe and an MER driver adapter to define and/or follow a desired intrabody trajectory. The trajectory frame assemblies include fins attached to the column support and a platform optionally with an X-Y table and/or arcuate reference brackets that are attached to the trajectory frame assemblies and can hold a reference frame with fiducials.

A surgical instrument positioning system includes articulating arms for coarse adjustment and a micro manipulator connectable to the articulating arms for fine adjustment. The micro manipulator selectively holds the surgical instrument and is operable to adjust the position of the surgical instrument. The micro manipulator includes two adjustment assemblies for providing linear adjustment and two adjustment assemblies for providing rotational adjustment. Features of the system also provide for control of the amount of free movement or play within the micro manipulator. Also a stop feature works in conjunction with the adjustment assemblies to maintain the tip of the instrument at an intersection of the two rotational axes facilitating rotational adjustment of the micro manipulator without linear displacement of the instrument tip.