Described are methods and compositions that provide for the production and use of generating synthetic or recombinant peptides having antifungal properties. Wherein a peptide or polypeptide consists or consists essentially of an anti-fungal portion of the alpha-7 domain of EntV, wherein the peptide or polypeptide comprises an amino acid sequence.

An antifouling coating composition, an antifouling coating film, a substrate with an antifouling coating film or a method for producing the same, an antifouling method for a substrate, or a method for repairing a substrate with an antifouling coating film. The antifouling coating composition includes a hydrolyzable copolymer (A) containing an organosiloxane block and a metal ester group, and zinc oxide (B). The copolymer (A) contains 5 to 25% by mass of a constituent unit derived from a metal ester group-containing monomer, 5 to 15% by mass of a constituent unit derived from a monomer represented by formula (2), and a constituent unit derived from a monomer represented by formula (3). ##STR00001##

An alkali-resistant water repellent member according to the present invention has: a silica layer on at least one surface of a base material, said silica layer having a film thickness of from 1 nm to 5 m, while containing 50% by mass or more of silica nanoparticles and 1% by mass or more of an organosilicon compound that has a plurality of silanol groups in each molecule; and a water repellent oil repellent layer on the outer surface of the silica layer, said water repellent oil repellent layer having a film thickness of from 0.5 nm to 30 nm, while being mainly composed of a cured product of a hydrolyzable fluorine-containing organosilicon compound. This alkali-resistant water repellent member is able to easily provide various base materials with a water repellent oil repellent coating film in a stable manner, said coating film having excellent alkali resistance and wet wear resistance.

A polymerizable quaternary ammonium compound (QAC) including an acrylate group and a cationic group is provided. Specifically, the acrylate group is capable of polymerization so as to integrate the QAC into a macromolecular chain of a polymer through an addition polymerization for introducing antimicrobial and antiviral activities. For instance, the polymerizable QAC can be polymerized with a vinyl group monomer, an acrylate monomer, a silane monomer, an adhesion monomer and an emulsification monomer to form a synthesized polymer emulsion. The polymer emulsion can be further incorporated into a coating material to provide a transparent, water resistant, antimicrobial and antiviral waterborne coating on a substrate's surface.