The present disclosure is directed to systems and methods for endovascular electroencephalography (EEG) and electrocorticography (ECoG) systems. In some embodiments, the disclosed systems include electrode arrays that are configured to record and/or stimulate brain tissue via placement within blood vessels of the brain. Venous and arterial EEG and ECoG electrodes, ambulatory EEG and ECoG systems, and transcutaneous access and signal control systems for general and ambulatory endovascular electroencephalography (EEG) and electrocorticography (ECoG), as well as endovascular neural stimulating electrodes are discussed.

A method comprises advancing a medical instrument toward a target within a patient anatomy, and the medical instrument includes a marker. The method further comprises depositing the marker at a location at or near the target along a trajectory of the medical instrument. The method further comprises sensing the marker to indicate a location of the target. The method further comprises, based on the marker, determining a second trajectory along which a treatment instrument may be advanced toward the target to treat the target. The second trajectory is different than the trajectory.

A vehicle suspension can include an adapter mounting face, a spindle rigidly mounted relative to the adapter mounting face, a wheel mounting hub including a hub body rotatably mounted on the spindle by bearings, and an adapter that spaces a brake component away from the adapter mounting face. Another vehicle suspension can include a spindle, bearings, and a wheel mounting hub rotatably mounted on the spindle by the bearings, the wheel mounting hub can include a hub body and a wheel mounting flange, the hub body and the wheel mounting flange being separate components of the wheel mounting hub. A system for adapting a vehicle suspension to different suspension capacities can include multiple wheel mounting hubs including a same hub body internal configuration configured to be rotatably mounted on the spindle by the bearings, but the wheel mounting hubs including respective different wheel mounting flanges.

Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Systems and methods for manufacturing and using magnetic resonance (“MR”) visible labels or markers to encode information unique to the subject or object being imaged by a magnetic resonance imaging (“MRI”) system are provided. The use of such MR-visible labels or markers enables unique information associated with the subject or object being imaged to be encoded into the images of the subject or object. This information can be used to anonymize protected health information (“PHI”); to provide detailed information about a surgical simulation device, quality assurance phantom, or the like; to provide spatial orientation and registration information; or so on.

Various implementations include a method of applying a surgery reference marker to skin of a patient. The method includes providing a medical scanner having at least one positioning laser; disposing the patient in a desired position relative to the medical scanner such that the at least one positioning laser illuminates a portion of the skin of the patient; disposing a temporary tattoo on the portion of the skin of the patient, the temporary tattoo having at least one positioning indicator configured to be applied to the skin of the patient, wherein the temporary tattoo is disposed such that the at least one positioning indicator indicates a position of the at least one positioning laser; and applying the temporary tattoo such that the at least one positioning indicator is transferred to the skin of the patient.

An endoluminal punch system including a sheath and dilator. The endoluminal punch may include energy delivery system capable of being transmitted from the proximal end to the distal end of the endoluminal punch to assist with tissue crossing and incisions. The dilator may include selectively deployable cutting mechanism to create incisions in tissue that are larger than their basic external diameter. The system may also be configured to reduce the risk of generating plastic emboli during insertion of the endoluminal punch.

Described herein are compositions comprising, a polymer; a non-physiological solution; and a visualization agent; wherein the polymer is soluble in the non-physiological solution and insoluble at physiological conditions. Methods of preparing the compositions are disclosed as well as methods of using these compositions to treat vascular conditions.

The present invention relates to a customized surgical guide device and a customized surgical guide generating method and program. A customized surgical guide generating method comprises the steps of: acquiring body surface data and treatment area data from medical image data by a computer; a first shape data generating step, wherein the first shape data is data which corresponds to the shape of the body part cover; a target point setting step of setting one or more target points; setting individual first points on the body surface accessible to the target point with a medical tool; setting a guide tube length on the basis of a distance from the first point to the target point; and generating final shape data in which one or more guide tubes are combined to the first shape data by applying the guide tube length to the first point.

A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).