Some embodiments provide systems, assemblies, and methods of analyzing patient anatomy including providing an analysis of a patient's spine. The systems, assemblies, and/or methods can include obtaining initial patient data, and acquiring spinal alignment contour information. Further, the systems, assemblies, and/or methods can assess localized anatomical features of the patient, and obtain anatomical region data. The system, assemblies, and/or method can analyze the localized anatomy and therapeutic device location and contouring. Further, the system, assemblies, and/or method can output localized anatomical analyses and therapeutic device contouring data and/or imagery on a display.

The invention relates to an optical navigation system for determining the position of a patient's anatomy of interest. The system comprises a locating device having at least two optical sensors and a patient reference having at least three optical markers. The system also comprises a reflecting device. When the line of sight between the patient reference and an optical sensor is intersected by an obstacle, the optical sensors are configured to measure, for each optical marker of the patient reference, a quantity representing the position of said optical marker in the frame of reference of the locating device from optical radiation originating from said optical marker and having a path reflected by the reflecting device to each optical sensor.

The invention relates to a method for displaying an injection point for a medical instrument. The method comprises the following steps: Providing at least one marker on a surface of an object, with such marker exhibiting the property that it can be recorded both tomographically, in particular fluoroscopically, and also optically; Generating tomographic image data that can be used to reconstruct a fluoroscopic image of the at least one marker, located on the surface of the object, together with the object; Determining the insertion point for the medical instrument on the surface of the object relative to the at least one marker in the coordinate system of the tomographic image data; Generating visual image data that can be used to reconstruct a visual image of the at least one marker, located on the surface of the object, together with the object; Transforming the coordinate of the insertion point in the coordinate system of the tomographic image data into the coordinate system of the visual image data using the relative position of the insertion point to the at least one marker; and Displaying the insertion point for the medical instrument in real time in a view of the object.

An intraluminal sensing device includes a catheter or a guidewire with a flexible elongate member that is positioned within a body lumen of a patient. The device also includes a sensor disposed at a distal portion of the flexible elongate member. The sensor obtains medical data associated with the body lumen while the flexible elongate member is positioned within the body lumen. The sensor is an ultrasound transducer, a pressure sensor, a flow sensor, and/or a temperature sensor. The device further includes a radiopaque marker coupled to the flexible elongate member. The radiopaque marker is an ultraviolet (UV) radiation-cured product of a mixture that includes a radiopaque material, an electromagnetic-radiation-curable adhesive, and a photoinitiator. The solution of the mixture is applied directly to the flexible elongate member and UV radiation-cured to form the radiopaque marker. The radiopaque marker is a band extending around a perimeter of the flexible elongate member.

An intraoperative ultrasound imaging system and method capable of using ultrasound imaging to safely place a surgical access instrument (e.g. guide wire, dilator, cannula, etc.) through a tissue (e.g., muscle, fat, brain, liver, lung, etc.) without damaging nearby neurovascular structure is described herein. The intraoperative ultrasound system includes an ultrasound probe assembly configured for emitting and receiving ultrasound waves and a computer system including a processor and a display unit. Once the probe is in position, ultrasound imaging is performed wherein the computer receives RF data from the probe and causes a B-mode image of the visible anatomical structures (e.g. muscle, bone, etc.) to be displayed on the display unit.

A method for creating a personalized stent or stent graft for a blood vessel with a saccular aneurysm includes: receiving a 3D model of the blood vessel with the saccular aneurysm; and generating a model of a personalized stent or stent graft that comprises a net shaped to fit along internal walls of the blood vessel and a covering positioned with respect to the net such as to cover an ostium of the aneurysm.

Methods and devices using measurements of heart electrophysiological activity to guide structural heart disease interventions. In some embodiments, measurements of heart electrophysiological activity are mapped into locations of a heart model defined by one or more additional measurement modalities. In some embodiments, the additional measurement modalities comprise impedance measurements. Locations to map electrophysiological data to, in some embodiments, are determined by non-electrophysiological measurements simultaneous with the electrophysiological data measurement which locate a probe—for example, measurements made by the probe itself, and/or measurements which themselves indicate positioning of the probe.

The invention relates to a system for planning introduction of a needle in a patient's body, comprising: a needle guide configured to be coupled to a needle; a localization system configured for tracking the needle guide with respect to the patient's body, the localization system being coupled to a needle tracker attached to the needle guide and a reference marker adapted to be attached to the patient's body to determine a spatial position and orientation of the needle tracker relative to the reference marker; a processor configured for determining a virtual position and orientation of the needle with respect to the 3D image using localization data of the needle guide, thereby defining a virtual needle having said virtual position and orientation, detecting a part of the needle that has already been inserted into the patient's body as a trace in the 3D medical image, computing a distance between the virtual needle and the detected needle, and determining a representation of the computed distance; a display coupled to the processor for displaying a representation of the virtual needle and the representation of the computed distance between the virtual needle and the detected part of the needle.

Provided are devices and methods for anesthetizing a patient undergoing surgery, and/or pain block procedures. In certain embodiments the disclosure provides a curved cryoneurolysis needle. In some forms, the methods include inserting at least one cryoneurolysis needle into a target region of the patient, and cooling the cryo-needle to inhibit the target intercostal nerve.

Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.