A marker delivery device includes a handle having a housing, and a cannula positioned in the handle that retractably extends beyond the front end of the housing. A retraction mechanism is mounted to the housing, and has a shear member. The retraction mechanism is coupled to a proximal end of the cannula. The retraction mechanism is configured to store a retraction force, and is configured to facilitate a retraction of the cannula into a chamber of the housing upon an actuation of the retraction mechanism. The shear member has a shear region of reduced cross section dimension. The shear member is configured to be displaced upon the actuation of the retraction mechanism to expose the shear region to the retraction force to shear the shear member at the shear region to enable the retraction and prevent reuse of the marker delivery device.

A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.

Marking device (100) for implantation into a tissue (260), having a support structure (102) which is formed by at least one elastic metal wire, is compressible and is self-expanding and which, in an expanded state, encompasses an interior space (104), characterized in that the marking device (100) is designed to transform itself on its own from a compressed state into an expanded state, even against a tissue pressure prevailing at a tissue site to be marked, and the marking device (100) in the expanded state has a hollow, approximately spherical shape.

Methods of performing surgical operations and associated devices are disclosed. An example method may include locating a first position on a first surface of a biological tissue; locating a second position on a second opposing surface of the biological tissue, the second position corresponding to the first position; and marking the second position on the second surface. The second surface may be generally opposite the first surface. An example method may include, after marking the second position, performing a therapeutic procedure on the biological tissue in the vicinity of the second position.

A surgical probe for augmenting artificial intelligence (AI) based anatomical recognition. Preferably the medical device probe is applied to any body cavity or space for which an image can be obtained and the medical device probe delivered to the target tissue captured on the image (i.e. endoscopic, arthroscopic, or other minimally invasive surgical procedures) in order to train and augment anatomical recognition models. The probe may provide reference points, markings, surface contours, size and scale representations, dye marking, spatial cues, light refraction, sonic propagation and other modalities for determining tissue properties and biomechanical characteristics. A data set of device probe augmented medical images and video are captured from the procedure and used to train the AI based recognition algorithms. The probe, which is designed with a machine-recognizable shaped tip and scale of reference markings, is manipulated by the surgeon to outline or “paint” specific tissue sites, explore tissue makeup, and provide other augmentations to the medical imaging dataset for AI recognition model development. The trained AI model provides immediate feedback with regard to anatomical feature identification, size, biomechanics, surgical guidance and disease state diagnosis.

A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

According to one embodiment, an apparatus is disclosed. The apparatus includes an endoscopic clip placement tool and one or more marking clips attached to a specimen mass by the clip placement tool to mark a margin and orientation of the specimen mass. A specimen marking clip is also provided that is adapted to selectively attach to tissue inside of a patient and corresponding tissue that has been excised from the patient for analysis. Sutures may be associated with the clips to help ensure correct in vivo and ex vivo sample orientation. In vivo clips may remain in the patient's body if necessary.

A lockable device, and methods for using said device, for inserting a marker into a patient's body. The device may be inserted into a patient's body in the locked state, transitioned into an unlocked state, and then used to deliver a marker to a precise location. The device may provide tactile and audible feedback once the marker has been placed and indicate that the device is ready for removal.

A marker delivery device includes a handle, an elongate cannula, a push rod assembly, and a plunger. The handle includes a first bore disposed within a portion of the handle. The elongate cannula extends distally from the handle along a longitudinal axis. The push rod assembly includes a mating feature. The push rod assembly is disposed within the first bore and extends distally through the cannula. The plunger is disposed within the first bore proximally of the push rod assembly and includes an engagement feature. The engagement feature is removably coupled to the mating feature. The engagement feature is configured to de-couple from the mating feature when the plunger translates the push rod assembly distally.

A gold marker recovery device for radiotherapy positioning and its using method comprises a positioning gold marker and a recovery clamp, the positioning gold marker comprises a gold marker body and an elastic fixed structure, the elastic fixed structure comprises a fixed segment, an extending segment and a spiral segment connected in sequence; the fixed segment is embedded in the gold marker body so that the fixed segment is closely connected with the gold marker body, A magnetic ball is arranged at one end of the gold marker body away from the extending segment; the recovery clamp comprises an operating handle, the rear end of the operating handle is connected with an outer sheath tube in a hollow structure, and the outer sheath tube is connected with a zipper for driving the clamp to open and close.