Disclosed is a system for assisting in guiding and performing a procedure on a subject. The subject may be any appropriate subject such as inanimate object and/or an animate object. The guide and system may include various manipulable or movable members and may be registered to selected coordinate systems.

Disclosed is a system for assisting in guiding and performing a procedure on a subject. The subject may be any appropriate subject such as inanimate object and/or an animate object. The guide and system may include various manipulable or movable members and may be registered to selected coordinate systems.

A medical lead includes a main body having a length extending from a proximal end to a distal end, a longitudinal axis parallel to the length, and a proximal portion adjacent to the proximal end and a distal portion adjacent to the distal end; a plurality of electrodes defining an electrode region; and an imaging marker positioned between the electrode region and the proximal end and separated from the electrode region by a distance in an axial direction. The imaging marker may include one or more marker segments. The imaging marker may be disposed in a pocket of a sleeve at least partially surrounding the main body and comprising one or more pockets for receiving the imaging marker. The medical lead may be operatively connected to an implantable medical device.

The present disclosure presents a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory. The trajectory array guide system can comprise: a base, an array guide, an imaging unit, and an elongated handle configured for connection with a stereotaxic navigation system. The present disclosure presents a method of using a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory.

Apparatus for performing a procedure using a tool configured to be advanced into a skeletal portion within a body of a subject along a longitudinal insertion path, and for use with: (a) a 3D imaging device configured to acquire 3D image data of the skeletal portion. (b) a 2D x-ray imaging device that is unregistered with respect to the subject's body and configured, while a portion of the tool is disposed at a first location along the longitudinal insertion path.

Systems and methods for tracking a target volume, e.g., tumor, in real-time during radiation treatment are provided. Under one aspect, a system includes an ultrasound probe, an x-ray imager, a processor, and a computer-readable medium that stores a 3D image of the tumor in a first reference frame and instructions for causing the processor to: instruct the x-ray imager and ultrasound probe to substantially simultaneously obtain inherently registered x-ray and set-up ultrasound images of the tumor in a second reference frame; establish a transformation between the first and second reference frames by registering the 3D image and the x-ray image; instruct the ultrasound probe to obtain an intrafraction ultrasound image of the tumor; registering the intrafraction ultrasound image with the set-up ultrasound image; and track target volume motion based on the registered intrafraction ultrasound image.

Apparatus, system and methods are described for providing a health care provider (HCP) with an enhanced reality perceptual experience for surgical, interventional, therapeutic, and diagnostic use. The apparatus, system and methods make use of a combination of sensors and audio visual data to cross-correlate information, and present the correlated information to the HCP on to one or more platforms for use during a diagnostic, interventional, therapeutic, or surgical procedure.

A position sensor has one or more fiducials formed of radio-opaque material and mounted along a surface of a radio-translucent body. A sensor element is coupled to the radio-translucent body and is spaced apart from the one or more fiducials and is energizable to acquire image content during receipt of exposure energy from an X-ray source to the position sensor. The sensor element is in signal communication with a processor and is energizable to generate data that is indicative of a relative position of the X-ray source. A radio-opaque covering is coupled against an outer surface of the radio-translucent body.

A marker includes a core and an outer region. The core has a first material with porous hydroxyapatite. The outer region completely covers the core, and has a second material with less porous hydroxyapatite, wherein ultrasonic or radiative imaging reveals a difference between the marker and tissue.

The invention describes the structure and use of passive Markers to indicate the position of suspicious lesions in tissue and a method to mark the lesions and margins of said suspicious lesions that facilitates the communication between the pathologist and the surgeon in order to excise the minimal amount of tissue from the diseased organ.