Water-in-oil (W/O) emulsion compositions having freeze-thaw stability are provided which include water, at least one hydrocarbon solvent, at least one nonionic emulsifier, and at least one freeze-thaw stabilizer which either prevents breaking of the emulsion after a freeze-thaw cycle or enables the emulsion to be re-formed following breaking after a freeze-thaw cycle by simple shaking of the emulsion composition. Preferred freeze-thaw stabilizers are polyols (e.g., glycerin), sugars (e.g., sucrose), polar aprotic solvents (e.g., dimethyl sulfoxide) and amphoteric compounds (e.g., lauryl dimethyl amine oxide). The freeze-thaw stabilizers are particularly useful in furniture care, shoe care and auto care cleaning and/or polishing products including therein water, hydrocarbon solvent(s), nonionic emulsifier(s) and additives, such as film former(s), surfactant(s), fragrance component(s) and preservative(s).

The present invention discloses a method for manufacturing a four-phase heavy-duty laundry detergent wipe, characterized by the following steps: (a) manufacturing a liquid starting laundry detergent solution which contains enzymes, surfactants and at least one polyvalent alcohol as a solubilizer and which is present in a liquid phase; (b) incorporating soap in the liquid starting laundry detergent solution to obtain a liquid laundry detergent solution (A), wherein the liquid laundry detergent solution is two-phase due to over-saturation; (c) admixing at least two different washing active solid components to the liquid laundry detergent solution (A) which are insoluble in the polyvalent alcohols of step a) to obtain a laundry detergent dispersion (B) which contains the liquid over-saturated two-phase laundry detergent solution (A) from step b) as a liquid continuous outer binary phase and the at least two washing active solid components as a solid phase; (d) applying the laundry detergent dispersion (B) to a solid carrier substrate (C) such that the final product is a four-phase system. Furthermore, a four-phase heavy-duty laundry detergent wipe is disclosed, comprising a solid carrier substrate (C) and a laundry detergent dispersion (B) which has been applied to the carrier substrate, characterized in that the laundry detergent dispersion contains a liquid over-saturated two-phase laundry detergent solution (A), which contains enzymes, surfactants and soap and at least one polyvalent alcohol as a solubilizer, as a liquid continuous outer binary phase and at least two different washing active solid components as a solid phase which is insoluble in the solubilizer.

Described herein is a process for a preparation of microcapsules based on cleavable multi-alcohols. Also described herein are cleavable multi-alcohol-based microcapsules. Also described herein are perfuming compositions and consumer products including such capsules, in particular perfumed consumer products in the form of home care or personal care products.

A cleaning solution, composition, and portable cleaner are provided that is all natural, safe, non-toxic, edible, anti-bacterial, anti-viral, anti-microbial, deodorizing, and further includes a pleasant fragrance and taste. In addition, the cleaning composition can be free from sugar, alcohol, surfactants, and other harmful or harsh ingredients. In addition, the cleaning composition allows for quick cleaning of any type of object that may be placed in the mouth, such as pacifiers, toys, candy, eating utensils, musical instruments, and mouth-pieces, among others.

The present disclosure relates to multi-purpose cleaning compositions, methods of manufacturing the multi-purpose cleaning compositions, and methods of using the multi-purpose cleaning compositions to clean a surface. Beneficially the multi-purpose cleaning compositions are capable of removing soil and providing antimicrobial activity. The compositions are especially useful on hard surfaces and are preferably low streaking.

The present disclosure relates to cleaning compositions and methods of deep cleaning surfaces and textiles. The cleaning compositions may include an enzyme having hexosaminidase activity and at least one perfume component.

The present invention relates to compositions such as cleaning compositions comprising enzymes. The invention further relates, use of compositions comprising such enzymes in cleaning processes.

A solid, particulate composition having at least one water-soluble carrier material, at least one fragrance and at least one water-miscible organic solvent, wherein the carrier material is a water-containing salt (hydrate) whose water vapor partial pressure at a specific temperature in the range from 30 to 100° C. corresponds to the H.sub.2O partial pressure of the saturated solution of this salt, such that the salt melts at this temperature in its own crystal water. The invention further relates to processes for producing the solid composition, and to a washing or cleaning product including the solid composition. In addition, the present invention also relates to the use of a washing or cleaning product of this kind for cleaning of textiles or hard surfaces, and corresponding methods of cleaning textiles or hard surfaces using a washing or cleaning product of this kind.

This provides a flexible and dissolvable solid sheet article containing a PVA polymer or copolymer having a weight average molecular weight of from 50,000 to 400,000 Daltons and a major surfactant selected from the group consisting of C.sub.6-C.sub.20 linear alkylbenzene sulfonates (LAS), alkoxylated sodium trideceth sulfates (STS), and combinations hereof.

Disclosed herein are compositions and methods of fixing and staining rare cells. Further, disclosed herein are methods of identifying circulating tumor cells (CTC). In some embodiments, the method includes: imaging a cell sample to identify a cell of interest; determining a first pixel intensity of a stained nuclear area; determining a second pixel intensity of a background area; calculating a ploidy status of the cell of interest by subtracting the second pixel intensity from the first pixel intensity; and determining whether the cell of interest is a CTC based on the ploidy status. The method may be computer implemented, such that the method uses a machine learning algorithm to identify a feature; process the feature to extract a parameter of interest; analyze the parameter of interest; and when the parameter of interest is greater than or less than a predetermined threshold, classify the cell of interest as a CTC.