To provide a technology that is noninvasive but can acquire information with high accuracy with a simple configuration.

Provided is a biological information acquisition device including a measurement unit that measures a radiation spectrum emitted from a measurement part, and an information processing unit that acquires biological information on the basis of a plurality of measurement results obtained from the measurement unit. Furthermore, also provided is a biological information acquisition system including a measurement apparatus that measures a radiation spectrum emitted from a measurement part, and an information processing apparatus that acquires biological information on the basis of a plurality of measurement results obtained from the measurement apparatus. Moreover, also provided is a biological information acquisition method including a measurement step of measuring a radiation spectrum emitted from a measurement part, and an information processing step of acquiring biological information on the basis of a plurality of measurement results obtained in the measurement step.

Disclosed herein are wearable bands for biomarker tracking and methods for making the wearable bands. The biomarker tracking wearable band having a printed circuit board assembly (PCBA), the PCBA including an electrocardiography (ECG) sensor utilizing printed Silver-Silver Chloride (Ag-AgCl) electrodes and an optical photoplethysmography (PPG) sensor utilizing more than two light emitting diodes (LEDs), and a directly over molded band encasing the PCBA.

An imaging system is provided comprising an imaging probe and at least one delivery device. The imaging probe comprises an elongate shaft, a rotatable optical core and an optical assembly. The elongate shaft comprises a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion. The rotatable optical core is positioned within the lumen of the elongate shaft and comprises a proximal end and a distal end. The rotatable optical core is configured to optically and mechanically connect with an interface unit. The optical assembly is positioned in the elongate shaft distal portion and proximate the rotatable optical core distal end. The optical assembly is configured to direct light to tissue and collect reflected light from the tissue. The imaging probe is constructed and arranged to collect image data from a patient site. The at least one delivery device is constructed and arranged to slidingly engage the imaging probe. Methods of introducing the imaging probe and the at least one delivery catheter into a patient are also provided.

A computer-implemented method for contact photoplethysmography, abbreviated contact PPG, comprises obtaining during a time interval plural PPG signals for sub-regions of a lens or video frame; and combining the plural PPG signals to thereby obtain a multi-region PPG signal.

The invention consists of a device to evaluate hemodynamic response generated by the spinal cord in response to a suprasensorial stimulus applied to a peripheral nerve (medium or posterior tibial) by the use of functional near-infrared spectroscopy (fNIRS). The device consists of 3 main components, an electrical stimulator, an optical recording unit and a signal processing and control module. The device allows non-invasive, comfortable, harmless, portable, home-based, and low-cost evaluation of changes in local hemodynamic parameters in response to neuronal activation of the spinal cord by electrical stimulation of a peripheral nerve. The invention also includes a corresponding method of using the device and monitoring the spinal function.

Provided is a biological information measuring instrument which can be easily and reliably worn on an appropriate position of an arm by a user. The biological information measuring instrument includes: a belt portion that is worn on a user's arm in a circumferential direction of the arm and disposed with a sensor for detecting a displacement of an arm muscle; and a case portion that is attached to a predetermined portion of the belt portion and houses a circuit component that processes a signal of the displacement detected by the sensor. The case portion has a shape of protruding from the belt portion in a longitudinal direction of the arm when the belt portion is worn on the arm, and amounts D1 and D2 of protrusions protruding in the longitudinal direction are different between one protrusion and the other protrusion.

A movable carrier auxiliary system includes a driver state detecting device and a warning device. The driver state detecting device includes a physiological state detecting module, a storage module, and an operation module. The physiological state detecting module is adapted to detect a physiological state of a driver. The storage module is disposed in a movable carrier and stores an allowable parameter corresponding to the at least one physiological state. The operation module is disposed in the movable carrier and is electrically connected to the physiological state detecting module and the storage module to detect whether the at least one physiological state of the driver exceeds the allowable parameter or not, and to correspondingly generate a detection signal. The warning device generate a warning message when the detection signal that the at least one physiological state of the driver exceeds the allowable parameter is received.

A device, a substrate including a connection port. The substrate includes traces to enable a circuit of the substrate. The circuit is connected to the connection port. A light sensor mechanically and electrically attached respectfully to a first planar surface of the substrate and the circuit. A light source is mechanically and electrically attached respectively to the first planar surface and the circuit. The light source is located lateral to the light sensor at a first distance. A light signal of the light source emanates from the light source at an angle perpendicular to the first planar surface and a reflector mechanically attached to the first planar surface and located between the light sensor and the light source. The light signal is substantially reflected by the reflector away from the light sensor.

The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

A system and method for adaptive illumination, the imaging system comprising an excitation source having a modulator, which generates a pulse intensity pattern having a first wavelength when the excitation source receives a modulation pattern. The modulation pattern is a data sequence of a structural image of a sample. An amplifier of the imaging system is configured to receive and amplify the pulse intensity pattern from the modulator. A frequency shift mechanism of the imaging system shifts the first wavelength of the pulse intensity pattern to a second wavelength. A laser scanning microscope of the imaging system receives the pulse intensity pattern having the second wavelength.