Disclosed are devices, systems and methods for in vivo monitoring of localized environment conditions within a patient user by measuring analytes, including glucose, oxygen, and/or other analytes. In some aspects, a sensor device includes a wafer-based substrate, at least one electrochemical sensor two-electrode contingent including a working electrode and a reference electrode on the substrate and configured to detect a target analyte in a body fluid when the sensor device is deployed within a subject's body, where the working electrode is functionalized by a chemical layer configured to facilitate a reaction involving the target analyte that produces an electrical signal; and an electronics unit in communication with the electrochemical sensor electrode contingent to transmit the electrical signal to an external processor.

A dry electrode and a physiological multi-parameter monitoring equipment are disclosed. The waterproof dry electrode comprises an encapsulation, extraction electrode and a contact surface layer, wherein the extraction electrode and the contact surface layer are connected with each other and disposed in the encapsulation; the contact surface layer comprises an exposed part and an embedded part encapsulation; the encapsulation comprises flexible silica gel and hard plastic portion, the embedded part being embedded into the hard plastic portion, and the hard plastic portion being packaged in the flexible silica gel. Through the above arrangement in the present invention, the dry electrode can reach a waterproof grade of IPX7, which is higher than living waterproof grade of an ordinary dry electrode. The PMPME can be a patch-type acquisition and monitoring equipment which is convenient for long time wearing and physiological multi-parameter monitoring, with excellent sealing and waterproofness, and the electrode is reusable.

The invention relates to a spirometer (1) comprising a MEMS-based thermal fluid flow sensor (13, 13.1, 13.2) for generating a signal in response to a fluid flow generated during inhalation or exhalation; and a microcontroller (14) for calculating the fluid flow from the signal generated by the flow sensor (13, 13.1, 13.2). The spirometer (1) may be connected to other devices, such as a smartphone or a personal computer or any other computing unit which is adapted to collect, store, analyse, exchange and/or display data. The invention further describes the use of the spirometer (1) in measuring a user's lung performance and/or monitoring it over time. Furthermore, the spirometer (1) may be provided in a system together with an air quality measurement device for determining the air quality at a location of interest; and a computing unit for collecting, analysing and correlating the user's lung performance data obtained from the spirometer (1) with the air quality data, and optionally geolocalisation data of said location.

A method of detecting changes in blood flow in a head of a subject includes measuring a value of a parameter of a cardiac bioelectrical signal at a scalp area of the subject relative to a reference cardiac bioelectrical signal. The method also includes comparing the value of the measured parameter with a predetermined value of the parameter to determine any change in blood flow in the head of the subject. The determined change can be used to detect changes in perfusion in the brain of a subject for example, as a result of anti-coagulation medication used to dissolve a clot in a blood vessel of the brain of a subject who has experienced ischaemic stroke.

The present invention relates to a portable breath gas and volatile substance analyzer comprising a breath input portion for inputting the breath into the analyzer by blowing breath, a breath delivery portion connected to the breath input portion, a breath storage portion connected to the breath delivery portion, a sensor provided in the breath storage portion for detecting the breath, and a microcontroller connected to the sensor for receiving the breath data from the sensor to analyze the gas and volatile substance data.

The present invention relates to a method for contactlessly measuring the amount of menstrual blood in a menstrual cup. The amount of menstrual blood that has been stored in a menstrual cup can be simply measured by using a contactless sensor means, thereby enabling the user to periodically check the amount of menstrual blood. This enables early detection and treatment of uterine fibroid, which may even lead to hysterectomy.

Systems, apparatuses, and methods for detecting and quantifying a fluid are described herein. In some examples, a sensor apparatus is used to absorb discharged fluid (or other fluid present). The sensor apparatus includes one or more sensors designed to provide a capacitance measurement using electrodes in the sensors and one or more fluid properties sensors that determine at least one fluid property of an absorbed fluid. The electrodes are designed using mirror image axes of deformation to minimize the effect of deformation caused by the wearer of the sensor while still allowing some degree of flexibility for comfort. The person wearing one or more of the sensors may be monitored and cared for remotely using a communication system between the local device and a remote device used by a caregiver or medical practitioner.

The face mask with temperature display is a filtering face mask with an integrated temperature display for displaying a measured temperature of the wearer. The face mask includes a filtering sheet having opposed front and rear faces, and at least one strap attached to the filtering sheet for securing the filtering sheet over a portion of a wearer's face in a manner similar to that of a conventional filtering face mask. A visual display is secured to the front face of the filtering sheet and a temperature sensor is secured to the rear face of the filtering sheet. The temperature sensor is in communication with the visual display, such that the visual display can display the measured body temperature of the wearer.

The wheal and flare analyzing system analyzes the mast cell reaction to an allergen being administered in a scratch or prick skin test. The system comprises a sensor array and a processing unit. The sensor array includes a plurality of emitters surrounding a receiver at the allergen test site. Energy of various wavelengths is emitted into the allergen test site. An energy receiver measures reflected various wavelengths from the plurality of emitters. A microprocessor is in digital communication with the plurality of emitters and the energy receiver. The reflected wavelengths have an energy return indicative of the intensity of the allergic reaction in the mast cells. The intensity of the allergic reaction is analyzable from the reflected wavelengths and other data over time. A plurality of temperature sensors measuring local dermal temperatures surrounding the sensor array, the local dermal temperature being indicative of the intensity of the allergic reaction.

This disclosure relates to diagnostic devices for diagnosing lymphedema. The diagnostic devices may include an array of sensors, which can at least include a durometer, temperature sensor, and dielectric sensor, to measure parameters of tissue. The measurements may be used to generate a tissue health score to diagnose lymphedema and monitor tissue heath.