An electronic device for providing biometric information is provided. The electronic device includes a sensor module, a memory, and a processor electrically connected to the sensor module and the memory. The processor obtains a biometric signal from the sensor module at a predetermined time interval, determines whether a user is in a first state on the basis of the obtained biometric signal, in case the user is in a first state, obtains a representative value for a respective of the at least one biometric signal, defines the obtained representative value for the respective of the at least one biometric signal as a candidate reference value for a corresponding biometric signal, determines a candidate reference value satisfying a predetermined condition as a first reference value for the corresponding biometric signal, and updates a second reference value previously configured for the corresponding biometric signal on the basis of the first reference value.

Provided herein are microelectrodes and methods of localizing and targeting the same. The microelectrodes include electrochemical or biological sensors, an array of electrical contacts along a long axis of the microelectrode, or both. The methods of localizing and targeting use statistical manipulations to reduce the errors inherent in spike train analyses.

A device and a method for metabolism monitoring of a user based on low-cost, energy-effective and ultra-compact metal-oxide semiconductor (MOS) sensor are provided. The device provides information on metabolism/nutrition/physical activity of the user based on measuring the MOS sensor resistance proportional to a ratio of oxygen (O2) to carbon dioxide (CO2) concentrations in exhaled air.

A biosensing device for continuous monitoring of an analyte in a fluid matrix includes an electromagnetic excitation element [402], a biosensing surface [406], an opposing surface [410], a separation component [420,422], light collection optics [412], a light sensor [414], an image recording and analysis system [416], and an excitation control system [400]. The separation component is connected to the biosensing surface and to the opposing surface, forming a concave gap region [408] between the biosensing surface and the opposing surface. The biosensing surface comprises biosensing particles sensitive to electromagnetic signals from the electromagnetic excitation element, where an optical response of the biosensing particles to the electromagnetic signals is adapted to change in the presence of an analyte in the gap region. The light collection optics couple light emitted from the biosensing particles on the biosensing surface to the light sensor. The image recording and analysis system is connected to the light sensor and processes light signals from the biosensing particles to determine presence or absence or concentration of the analyte in the fluid matrix.

The present disclosure relates to systems and methods for activating a circuit of an implant device. Consistent with one implementation, an implant device is provided with a sensor including a working electrode (WE) and a counter electrode (CE). The sensor may be configured to generate a first current at the CE when the implant device is implanted in a body of a subject. A sensing circuit may also be provided that is electrically coupled to the WE of the sensor. The sensing circuit may be activated based on the first current and utilize the sensor to measure one or more parameters of an individual or other subject.

A device for illuminating a posterior segment of an eye may include multiple channels. Each of the channels may include multiple illumination paths such as a first region illumination path, and a second region illumination path. The first region illumination path and the second region illumination path may be illuminated at different times such that a first region and a second region may be imaged without interference from a non-illuminated illumination path.

A system and method for non-invasively measuring at least one analyte within a blood vessel is provided. The system includes an excitation light source having at least one excitation laser configured to selectively produce an excitation light beam, an interrogation light source having at least interrogation laser configured to selectively produce an interrogation light beam at a predetermined interrogation wavelength, a Fabry-Perot sensor configured to be transparent to excitation light, and to reflect interrogation light, at least one light beam steering device, a light detector, and a controller in communication with the excitation light source, the interrogation light source, the at least one light beam steering device, the light detector, and a memory storing instructions.

A method for monitoring feeding maturation in premature babies, the method including measuring an acoustic response from a baby during a selected time period to provide acoustic information; comparing the measured acoustic response against a train data set to determine an indication of a swallow event; and measuring a respiration pattern of the baby during a swallow cycle using a peak and valley model to provide respiration data, where a feeding maturity of the baby is determinable in dependence on the swallow indication and respiration data.

Disclosed is a stent-mesh and microelectrode assembly that is deployable using a catheter or cannula to form a neural interface for recording and/or stimulation of neural tissue. In some embodiments, the assembly may include a thin-film microelectrode array attached to a spring-like stent-mesh component. The thin-film microelectrode array may include an electrode body having two lateral wing-like appendages located distal to a thin-film flexible cable that terminates at the proximal end in a thin-film connector region. The stent-mesh may be attached to the thin-film microelectrode array and configured to be advanced to a target area in a collapsed state and then expanded after reaching the target area to transition the thin-film microelectrode array to a deployed configuration. Accordingly, the assembly may deliver the thin-film microelectrode array to a target area in a minimally invasive manner.

An intracellular monitoring device (IMD) that fits completely inside a living cell, and causes no significant impairment, to a cell's normal biological processes. The IMD monitors a cell for its level of a biological substance (e.g., calcium ion concentration) of interest. If the biological substance reaches or exceeds a threshold, the IMD transmits an electromagnetic signal, received by an antenna outside the cell. Each IMD has its electromagnetic signal encoded with a unique frequency. Detection of the frequency components, in the signals received by an antenna, permits identification of the source IMD's. A high calcium ion concentration is indicative of a strongly-activated cerebral cortex neuron. Brain tissue is relatively transparent to near infrared, making it a good frequency band, for the electromagnetic signals from neuron-monitoring IMD's. The near infrared of each IMD can be produced by quantum dots, powered by bioelectric catalysis triggered by high calcium ion concentration.