Disclosed herein are improved neural depth probes for detection and stimulation, along with various related improved components, devices, methods, and technologies. More specifically, the devices are layered depth electrodes with at least two layers, with each of the layers containing at least one thin-film trace disposed thereon. Each of the devices can also have a plurality of layers with at least two traces on each layer and contacts coupled to each trace.

A flexible and/or stretchable structural system for transmitting electrical signal between first and second rigid portions comprises a body structure and said first and second portions arranged to said body structure. The modulus of elasticity of said first portion is lower than the corresponding modulus of elasticity of said second portion. In addition the modulus of elasticity of said body structure is lower than the corresponding modulus of elasticity of said second portion. The system comprises also an interface portion, such as e.g. an electrically conducting fabric, textile or knit, which is arranged to said body structure and between said first and second portions. The interface portion electrically connects said first and second portions. The modulus of elasticity of said interface portion is lower than the corresponding modulus of elasticity of said second portion.

Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

An apparatus includes a modular colpotomy cup component and a modular shaft component. The modular colpotomy cup component includes a proximal base, an elongated sleeve, an expanding member, and a colpotomy cup. The proximal base is configured to couple to a distal end of a head of a robotic arm. The modular shaft component includes a coupling body and an elongated shaft. The coupling body is configured to couple to the head of the robotic arm such that the modular shaft component and the modular colpotomy cup component are attached to each other via the head of the robotic arm. The elongated shaft extends distally from the coupling body and is configured to be inserted through the opening of the proximal base such that the coupling body is configured to couple to the head of the robotic arm.

Medical devices are provided, comprising a medical device and a sensor.

Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.

An optical connector including a first optical fiber having a first diameter and having a core that includes a thermally expanded core portion adjacent a first end of the first optical fiber, a second optical fiber spliced to a second end of the first optical fiber, the second optical fiber having a second diameter less than the first diameter, and a connector bore having a first bore portion configured to receive the first end of the first optical fiber.

Methods and systems are provided for obtaining cleaned sequences showing trajectories of movement of a center of gravity and for estimating a biometric information pattern or value of a target. One of the methods includes removing noises from initial sequences showing trajectories of movement of a center of gravity to obtain the cleaned sequences. Another one of the methods includes reading cleaned sequences of the target into a memory, extracting features from the cleaned sequences, and estimating a biometric information pattern or value of the target from the extracted features, using a classification or regression model of biometric information patterns or values. The biometric information pattern may be a pattern derived from respiratory or circulatory organs of a target.

Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.