C12N15/77

Method for producing 3-fucosyllactose using <i>Corynebacterium glutamicum</i>

Disclosed is a method for producing 3-fucosyllactose using a wild Corynebacterium glutamicum strain. In addition, using the Corynebacterium glutamicum strain, which is a GRAS strain, 3-fucosyllactose can be produced at a high concentration, high yield and high productivity.

Method for producing 3-fucosyllactose using <i>Corynebacterium glutamicum</i>

Disclosed is a method for producing 3-fucosyllactose using a wild Corynebacterium glutamicum strain. In addition, using the Corynebacterium glutamicum strain, which is a GRAS strain, 3-fucosyllactose can be produced at a high concentration, high yield and high productivity.

Modifications to lysine decarboxylase enzymes

The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mutant polypeptides, and methods of generating such microorganism.

Modifications to lysine decarboxylase enzymes

The invention provides CadA polypeptides with mutations that increase activity in alkaline pH compared to the wild-type lysine decarboxylase. The invention also provides methods of generating such mutant polypeptides, microorganisms genetically modified to overexpress the mutant polypeptides, and methods of generating such microorganism.

Polypeptide and method of producing IMP using the same

The present disclosure relates to a novel polypeptide having an activity of exporting 5′-inosine monophosphate, a microorganism comprising the same, a method for preparing 5′-inosine monophosphate using the same, and a method for increasing export of 5′-inosine monophosphate.

Modified polypeptide with attenuated activity of citrate synthase and method for producing L-amino acid using the same

The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.

MODIFIED POLYPEPTIDE WITH ATTENUATED ACTIVITY OF CITRATE SYNTHASE AND METHOD FOR PRODUCING L-AMINO ACID USING THE SAME
20230046561 · 2023-02-16 ·

The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.

VARIANT DIHYDRODIPICOLINATE REDUCTASE POLYPEPTIDE AND METHOD OF PRODUCING L-THREONINE USING THE SAME
20220356480 · 2022-11-10 ·

The present disclosure relates to a variant polypeptide having attenuated dihydrodipicolinate reductase activity and a method of producing L-threonine using the same.

VARIANT DIHYDRODIPICOLINATE REDUCTASE POLYPEPTIDE AND METHOD OF PRODUCING L-THREONINE USING THE SAME
20220356480 · 2022-11-10 ·

The present disclosure relates to a variant polypeptide having attenuated dihydrodipicolinate reductase activity and a method of producing L-threonine using the same.

MODIFIED POLYPEPTIDE OF MESO-DIAMINOPIMELATE DEHYDROGENASE AND METHOD FOR PRODUCING L-THREONINE USING THE SAME
20220356479 · 2022-11-10 ·

The present disclosure relates to a modified polypeptide, in which the activity of meso-diaminopimelate is weakened, and a method for producing L-threonine using the same.