Transdermal microneedles continuous monitoring system is provided. The continuous system monitoring includes a substrate, a microneedle unit, a signal processing unit and a power supply unit. The microneedle unit at least comprises a first microneedle set used as a working electrode and a second microneedle set used as a reference electrode, the first and second microneedle sets arranging on the substrate. Each microneedle set comprises at least a microneedle. The first microneedle set comprises at least a sheet having a through hole on which a barbule forms at the edge. One of the sheets provides the through hole from which the barbules at the edge of the other sheets go through, and the barbules are disposed separately.

A system for imaging a target embedded in a scattering media includes: one or more light sources that are pulsed lights at one or more wavelengths in a range of visible to near-infrared; a detector, including a photodetector array with a time-gating function, configured to collect a scattered light after a gate start time; and a processor configured to determine an image of the target based on the scattered light.

A wearable device and a method of operating the same are provided. The wearable device includes a shoe assembly, a plurality of pressure sensors, a processing circuit and an alarm module. The plurality of pressure sensors are disposed on the shoe assembly and configured to generate a plurality of pressure sensing values. The processing circuit is configured to calculate a center of gravity coordinate according to the plurality of pressure sensing values and coordinates of the plurality of pressure sensors, and generate a determination result according to the center of gravity coordinate. The alarm module is configured to output an alarm signal to perform an alarm function.

A smartphone or other mobile computer device, general purpose or specialized, wherein the smartphone device is configured to actively control the configuration of one or more bladders, compartments, chambers or internal sipes and one or more sensors located in either one or both of a sole or a removable inner sole insert of the footwear of the user and/or located in an apparatus worn or carried by the user, glued unto the user, or implanted in the user. The one or more bladders, compartments, chambers, or sipes, and one or more sensors are configured for computer control. A sole and/or a removable inner sole insert for footwear, including one or more bladders, compartments, chambers, internal sipes and sensors in the sole and/or in a removable insert; or on an insole; all being configured for control by a smartphone or other mobile computer device, general purpose or specialized.

A system for assessing laxity of a joint of a patient is disclosed. The system comprises a tensioner tool having a substantially rigid portion that may be inserted within the joint to apply a force against a bone surface thereof. The system further comprises a tensioner sock having a flexible body with an opening to receive the tensioner tool and a sensor array disposed on the flexible body. Each sensor of the sensor array is configured to contact the bone surface and detect a pressure when the force is applied against the bone surface. The system further comprises a processor configured to receive the detected pressure from each sensor and calculate the force applied to the bone surface based on the detected pressures.

A method for obtaining a near-infrared spectroscopy (fNIRS) cerebral signal in a subject includes: placing a near-infrared emitter and respective proximal and distal near-infrared detectors on a skin of a head of a subject; during a baseline recording stage with the subject in resting-state, record near-infrared signals, the recorded signals including a baseline deep-signal and a baseline shallow-signal; calculate a scaling factor between amplitudes of the baseline deep-signal and the baseline shallow-signal at a given task-frequency; with the subject undergoing a cyclic cerebral stimulation at the task-frequency during a stimulation recording stage, record near-infrared signals, the recorded signals comprising a shallow-signal and a deep-signal; and applying the scaling factor to the shallow-signal, calculating the cerebral signal at the task-frequency as a difference between the deep-signal and the scaled shallow-signal, at the task-frequency.

A biofeedback system for monitoring a limb of an animal. The biofeedback system comprises a non-rigid wrap configured to encircle the limb when the non-rigid wrap is attached to the limb and a plurality of sensors configured to be disposed within an interior of the non-rigid wrap when the non-rigid wrap is attached to the limb. Each of the plurality of sensors measures a first biometric value. The biofeedback system further includes a control module disposed within the interior of the non-rigid wrap and coupled to the plurality of sensors. The control module reads from each of the plurality of sensors first biometric values recorded during exercise of the animal.

An apparatus for measuring patient data includes a frame having a plurality of electrode hubs. Each hub can include one or more electrode members. The frame can be configured to receive a head of a patient. Each of the electrode hubs can have a single electrode member or a plurality of electrode members that extend from or are connected to an outer member for contacting a scalp of the head of the patient. The outer member can have at least one circuit configured to transmit data received by at least one of the electrode members to a measurement device via a wireless communication connection (e.g. Bluetooth, near field communication, etc.) or a wired communication connection.

A breast milk flow monitoring system in the form of a milk flow monitoring sensor is described and includes an array of electrodes and a controller. The electrodes include electrically conductive surfaces that are arranged to contact a skin surface of a breast. The controller generates a first excitation signal that is communicated via the first electrode to a first location on the breast, and generates a second excitation signal that is communicated via the first electrode to the first location on the breast. The controller receives a first current response signal and a second current response signal. A bio-impedance spectroscopic analysis of the first current response signal and the second current response signal is executed, wherein the bio-impedance spectroscopic analysis is calibrated for breast milk flow. A breast milk flow parameter is determined based upon the bio-impedance spectroscopic analysis.

Certain aspects of the disclosure are directed to an apparatus including a scale and external circuitry. The scale includes a platform, and data-procurement circuitry for collecting signals indicative of the user's identity and cardio-physiological measurements. The scale includes processing circuitry to process data obtained by the data-procurement circuitry, therefrom generate cardio-related physiologic data, and to send user data to the external circuitry. The external circuitry identifies a risk that the user has a condition based on the reference information and the user data provided by the scale and outputs generic information correlating to the condition to the scale that is tailored based on the identified risk.