C12N2500/16

COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION

Provided herein are methods and compositions comprising a bacterium or a metabolite thereof for enhancing mitochondrial and/or peroxisomal function.

COMPOSITIONS AND METHODS FOR MAXIMIZING MALONYL-COA IN E. COLI

Disclosed herein is a low-cost method to maximize malonyl-CoA production in E. coli, and consequently a high yield of its derived bioproducts.

Method for bioremediation of lead

The present disclosure provides methods and compositions of matter directed to removing heavy metals, such as lead, from aqueous solutions by bioremediation. The methods use bacteria, which thrive in the presence of heavy metals to precipitate the heavy metals from the aqueous solution. In some embodiments, the bacteria comprise Bacillus licheniformis.

COMPOSITIONS AND METHODS FOR IMPROVED GAMETE VIABILITY AND FUNCTION
20200347347 · 2020-11-05 ·

The present specification provides for a media composition that provides enhanced viability and activity to sperm cells.

MEDIA COMPOSITIONS FOR NEURONAL CELL CULTURE

Provided herein are, inter alia, are media compositions useful for culturing neural cells. In particular, the compositions provided herein mimic important physiological conditions in the living brain and sustain neural activity. The media compositions provided herein improve the efficiency of human neuron maturation and promote synaptic function in long-term in vitro cultures.

COMPOSITIONS INCLUDING ENUCLEATED ERYTHROID CELLS
20200338129 · 2020-10-29 ·

Provided herein are compositions including enucleated erythroid cells and methods of making and using the same.

CULTURE MEDIUM FOR PLURIPOTENT STEM CELLS
20200332263 · 2020-10-22 · ·

The present invention relates to a chemically defined medium for eukaryotic cell culture, comprising water, at least one carbon source, one or more vitamins, one or more salts, one or more fatty acids, one or more buffer components, selenium, at least one substance of the group of Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) and at least one polypeptide of the GF- superfamily with the ability to inhibit stem cell differentiation, its use in the culture of human pluripotent stem cells, a cell culture system comprising human pluripotent stem cells and the chemically defined medium, as well as a kit for proliferation and/or maintenance of human pluripotent stem cells.

Use of ion concentrations to increase the packaging efficiency of recombinant adeno-associated virus
10801042 · 2020-10-13 · ·

The present invention is directed to methods for increasing the efficiencies with which recombinant adeno-associated virus (rAAV) are packaged, so as to increase their production titers. More specifically, the invention relates to a method for increasing the production titer of rAAV by transfected cells by increasing the ionic strength of the cell culture media through the administration of additional ions.

Cosmetic composition for improving condition of skin, containing cell culture medium, epidermal growth factor and bovine serum albumin

The present invention relates to: a cosmetic composition for improving the condition of the skin, containing, as active ingredients, a cell culture medium, an epidermal growth factor and a bovine serum albumin; a method for improving the condition of the skin by using the same; and a method for preventing or treating skin diseases. According to the present invention, the cosmetic composition can exhibit excellent wrinkle-reducing and wound-healing effects even when only a small amount of EGF is used, and thus can be useful in improving the condition of the skin or in preventing or treating skin diseases.

Salt formulations for the fermentation of marine microorganisms

Growth medium are disclosed for use in fermenting a marine microorganism. The medium comprise Potassium, Calcium, Strontium, Borate and Fluoride at specific concentrations. Alternatively, the growth medium comprises cobalt at specified concentrations or comprises vitamin B.sub.12 at specified concentrations. Methods of producing certain desired compound by fermentation of a marine microorganism are also disclosed.