An implantable capsule includes a capsule, an adsorption hole, a pH detector, two impedance sensors and a pose sensor. The capsule includes a first shell, a second shell and the first shell and the second shell defines an accommodating space. The adsorption hole is disposed at the first shell and attaches to the tube wall of the esophagus by the external force. The pH detector is disposed at the second shell to measure the pH value of the esophageal fluid. Two impedance sensors are disposed at the first shell and the second shell. The two impedance sensors measure the impedance of the esophageal fluid to determine the fluid direction of the esophageal fluid. The pose sensor is disposed at the second shell to determine the patient pose. By this configuration, lightweight and wireless gastroesophageal monitoring device and the long-time measurement of pH of the esophageal fluid may be achieved.

Embodiments of the present disclosure include a handheld multi-parameter patient monitor capable of determining multiple physiological parameters from the output of a light sensitive detector capable of detecting light attenuated by body tissue. For example, in an embodiment, the monitor is capable of advantageously and accurately displaying one or more of pulse rate, plethysmograph data, perfusion quality, signal confidence, and values of blood constituents in body tissue, including for example, arterial carbon monoxide saturation (“HbCO”), methemoglobin saturation (“HbMet”), total hemoglobin (“Hbt”), arterial oxygen saturation (“SpO2”), fractional arterial oxygen saturation (“SpaO2”), or the like. In an embodiment, the monitor displays a line associated with a patient wellness level.

Aspects of the present disclosure include a sensor configured to store in memory indications of sensor use information and formulas or indications of formulas for determining the useful life of a sensor from the indications of sensor use information. A monitor connected to the sensor monitors sensor use and stores indications of the use on sensor memory. The monitor and/or sensor compute the useful life of the sensor from the indications of use and the formulas. When the useful life of the sensor is reached, an indication is given to replace the sensor.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

A method for dynamically switching blood pressure measurement model, adapted to a wearable blood pressure measurement device with a biosignal sensing assembly and a processor, wherein said biosignal sensing assembly comprises two exposed electrodes, comprises: obtaining potential difference by said two exposed electrodes; determining whether potential difference is smaller than potential threshold by processor; obtaining first biosignal of specified user by biosignal sensing assembly when potential difference is smaller than the potential threshold; calculating first blood pressure value by processor according to at least first biosignal and first blood pressure model and outputting first blood pressure value; obtaining second biosignal of specified user by biosignal sensing assembly when potential difference is not smaller than the potential threshold, wherein types of first and second biosignal are different; and calculating second blood pressure value by processor according to second biosignal and second blood pressure model and outputting second blood pressure value.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.