Amyloid fibers-based electrodes and apparatuses comprising the same. Additionally, methods for manufacturing amyloid fibers-based electrodes.

This sensor is for measuring an analyte and has a probe to be inserted inside a living body. The probe of the sensor includes a substrate, an electrode formed on the substrate, and a reagent layer that contains an oxidoreductase and that is formed on the electrode. At at least one end of the probe in the width direction, the reagent layer and the electrode are trimmed along the insertion direction of the probe toward the inside of the living body.

A disposable spiral electrode for a fetal scalp, comprising an electrode fixing column (6), a spiral electrode and an auxiliary electrode (6.1, 6.3) which are on the electrode fixing column (6), a twisted pair (4), an inner sleeve (8), an outer sleeve (1) and an outer sleeve fixing piece, wherein one end of the outer sleeve (1) is inserted into the outer sleeve fixing piece; the electrode fixing column (6) extends out of or retracts into the other end of the outer sleeve (1); one end of the twisted pair (4) sleeved with the inner sleeve (8) is respectively connected to the spiral electrode and the auxiliary electrode (6.1, 6.3), and the other end thereof is led out from within the outer sleeve fixing piece; an outer sleeve (2) in the outer sleeve fixing piece is movably sleeved on an inner sleeve (5) and may move relatively along the axial direction; one end of the outer sleeve (2) is in insertion connection with one end of the outer sleeve (1); a section of an inwardly concave arc (3.1) is arranged on a wire pressing ring (3) movably connected to one end of the inner sleeve (5); a groove (5.3) is formed in the edge of an end opening of the inner sleeve (5), and the wire pressing ring (3) is buckled on the end opening of the inner sleeve (5); and the inwardly concave arc (3.1) and the groove (5.3) form a meshing opening that clamps the twisted pair (4). The telescoping of the spiral electrode is convenient to control and accurate, and the twisted pair (4) is convenient to fix and reliable. The shape design of the electrode fixing column (6) is reasonable and safe to use.

A medical electrode device for implantation comprises a carrier formed from an electrically insulating material and defining a surface extending along a plane of extension, and at least one electrode arranged on the carrier for emitting an electrical stimulation signal and/or receiving an electrical sense signal. The at least one electrode comprises first and section wall sections. Said first wall section, in a cross-section along a cross-sectional plane perpendicular to said plane of extension, extends straight along a perpendicular direction with respect to said plane of extension or at an oblique angle with respect to said perpendicular direction, the first wall section in contact with the carrier electrically insulating material. Said second wall section, in said cross-section along said cross-sectional plane perpendicular to said plane of extension, adjoins said first wall section and is curved, the second wall section not in contact with the carrier electrically insulating material.

One embodiment of the present invention provides a flexible neural electrode having improved adherence to an object by using a three-dimensional structure. A neural electrode based on the three-dimensional structure of a flexible substrate, according to one embodiment of the present invention, comprises: a first polymer layer, which is formed from a polymer material, is flexible, and functions as a base; at least one photoresist part, which is formed on one portion of the surface of the first polymer layer and forms a three-dimensional structure; a second polymer layer which is formed on the photoresist part and the rest of the surface of the first polymer layer, and which comprises protrusion parts caused by the photoresist part; a metal thin film layer formed by patterning a metal thin film on the surface of the second polymer layer and the surface of the protrusion parts; and a third polymer layer which is formed on the surface of the second polymer layer and the metal thin film layer so as to function as a covering, and which comprises measurement holes formed so that one portion of the metal thin film layer formed at the ends of the protrusion parts is exposed to the outside.

An interface structure for a biological environment including at least one composite electrical impulse generating layer comprising a matrix phase of a piezo polymer material, a first dispersed phase of piezo nanocrystals, and second dispersed phase of carbon nanotubes, the first and second dispersed phase presented through the matrix phase. The piezo polymer material and piezo nanocrystal convert mechanical motion into electrical impulses and accept electrons to charge the composite impulse generating layer. The carbon nanotubes provide pathways for distribution of the electrical impulses to a surface of the composite impulse generating layer contacting the biological environment. The carbon nanotubes further provide for the delivery of the byproducts of the free radical degradation from the biological environment to both piezo-nanocrystals and piezo-polymer.

Embodiments of the invention provide methods and materials for making analyte sensors having a plurality of layered elements such as amperometric glucose sensors that are used by diabetic individuals to monitor blood sugar concentrations. Embodiments of the invention utilize plasma deposition technologies to form thin films of hexamethyldisiloxane useful in such sensors. Sensors that incorporate the thin film compositions formed by these processes exhibit a number of desirable characteristics.

The present invention provides a bio-electrode composition including a silicone bonded to a sulfonimide salt, wherein the sulfonimide salt is shown by the following general formula (1): ##STR00001##
wherein R.sup.1 represents a linear, branched, or cyclic alkylene group having 1 to 20 carbon atoms optionally having an aromatic group, an ether group, or an ester group, or an arylene group having 6 to 10 carbon atoms; Rf represents a linear, branched, or cyclic alkyl group having 1 to 4 carbon atoms and containing at least one fluorine atom; M.sup.+ is an ion selected from a lithium ion, a sodium ion, a potassium ion, and a silver ion. This can form a living body contact layer for a bio-electrode that is excellent in electric conductivity and biocompatibility, light-weight, manufacturable at low cost, and free from large lowering of the electric conductivity even though it is wetted with water or dried.

The present disclosure provides an electronic device and method of manufacturing the same. The electronic device includes a first region, a second region, an electronic component, and a first sensing element. The second region is adjacent to the first region. The first region has a first pliability. The second region has a second pliability. The second pliability is greater than the first pliability. The electronic component is disposed at the first region. The first sensing element is disposed at the second region and electrically connected to the electronic component.

Presented herein are gas permeable, ultrathin, stretchable epidermal electronic devices and related methods enabled by self-assembled porous substrates and conductive nanostructures. Efficient and scalable breath figure method is employed to introduce the porous skeleton and then silver nanowires (AgNWs) are dip-coated and heat-pressed to offer electric conductivity. The resulting film has a transmittance of 61%, sheet resistance of 7.3 Ω/sq, and water vapor permeability of 23 mg cm.sup.−2 h.sup.−1. With AgNWs embedded below the surface of the polymer, the electrode exhibits excellent stability with the presence of sweat and after long-term wear. The present subject matter demonstrates the potential of the electrode for wearable applications—skin-mountable biopotential sensing for healthcare and textile-integrated touch sensing for human-machine interfaces. The electrode can form conformal contact with human skin, leading to low skin-electrode impedance and high-quality biopotential signals. In addition, the textile electrode can be used in a self-capacitance wireless touch sensing system.