A header-less implantable medical device, system and method are provided. The device includes an electronics module including circuitry, a battery, a receptacle assembly having an interior chamber and a receptable inlet configured to receive a lead connector assembly. A device housing has a case body that includes side walls and a peripheral edge that defines a single common chamber. The electronics module, battery and receptacle assembly are provided within the single common chamber. A connector opening is provided in the case body and joined to the receptacle inlet to form a passage through the case body into the interior chamber of the receptacle assembly.

The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also measure the conditions of the environment surrounding the system.

A medical device includes a hybrid circuitry assembly and a core circuitry support structure. The core circuitry support structure includes a frame defining a cavity configured to receive at least a portion of the hybrid circuitry assembly. An outer surface of the frame is shaped to correspond to an inside surface of a core assembly housing configured to enclose the hybrid circuitry assembly and the core circuitry support structure.

A capsule adapted to be introduced into the digestive system and gastrointestinal (GI) tract of a mammal which consists of a capsule shaped container consisting of a wall material capable of being bio compatible with the digestive system and being adapted to protect the electronic and sensor devices contained in the capsule. The capsule contains gas composition sensors operable at several temperature points for a short duration, a temperature sensor, a micro controller, a power source and a wireless transmission device. The capsule wall incorporates gas permeable membranes adjacent said gas sensors. The microprocessor is programmed to receive data signals from the sensors and convert the signals into gas composition and concentration data and temperature data suitable for transmission to an external computing device.

A system and method for facilitating a cardiac rhythm disorder diagnosis based on subcutaneous cardiac monitoring data with the aid of a digital computer are provided. Cutaneous action potentials of a patient are recorded as electrocardiogram (EGC) data over a set time period using a subcutaneous insertable cardiac monitor. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks and the associated heart rates in the R-R interval plot.

Apparatus for determining data indicative of blood oxygen levels of internal organs are disclosed. The apparatus comprising: a body comprising a contact surface for engaging with a subject in a vicinity of an internal organ of the subject; the body defining a first recess and second recess, the first and second recesses extending from the contact surface into the body, the second recess being separate from the first recess; a light source comprising a light emitting region located within the first recess and configured to emit light of at least two discreet wavelengths from the first recess of the body onto the internal organ; and a photo-detector comprising a light sensitive region located within the second recess and configured to detect light received at the second recess, wherein the detected light comprises the emitted light reflected from a region of a subject in proximity to an internal organ; wherein the apparatus is configured such that the light emitting region and the light sensitive region are set back from the contact surface by from about 1 mm to about 20 mm and nearest points of the light emitting region and the light sensitive region are separated from one another by from about 4 mm to about 20 mm, such that the detected light is indicative of blood oxygen levels in blood vessels of an outermost surface of the internal organ. Also disclosed are systems comprising the apparatus and methods utilising it for assessing internal organ health of a subject and in particular, but not exclusively, for determining blood oxygen saturation in internal organs of a subject.

Embodiments herein relate to implantable medical devices including a welded joint with reduced residual stress. In a first aspect, an implantable medical device is included having a power subunit comprising a first biocompatible electrically conductive shell, an anode disposed therein, a cathode disposed therein, and a lid. The implantable medical device can further include an electronics control subunit comprising a second biocompatible electrically conductive shell, and a control circuit disposed therein. Both of the first and second biocompatible electrically conductive shells can include first and second opposed wide sides, first and second opposed narrow sides, and four rounded corners. The first shell can be welded to the lid around a perimeter thereof forming a weld line. The weld line can have a weld line terminus and the weld line terminus can be positioned on a narrow side or a rounded corner. Other embodiments are also included herein.

An imaging capsule including, a radiation source, a collimator that blocks the emission of radiation from the radiation source except through one or more output columns, a shutter comprising one or more openings; wherein the shutter is rotatably coupled to the collimator to enable selecting at least two states; a closed state in which the shutter blocks the emission of radiation from the radiation source, and an open state in which the shutter does not block the emission of radiation, a motor configured to rotate the collimator and select the state of the shutter, a main power source configure to power the motor, a circuit that monitors a status of the main power source and instructs the motor to place the shutter in the closed state if power in the main power source is below a threshold value.

Disclosed are systems and methods for detecting analyte levels. These systems and methods may include a sensor configured for at least partial placement in an analyte-containing medium. The sensor may include one or more transducers and one or more diffusion barriers. The diffusion barriers may be arranged to delay diffusion of analyte to one transducer relative to another transducer. This delay may be used for purposes such as calculating and/or compensating for lag between a measured analyte level and a physiological analyte level of interest.

The present disclosure includes ingestible devices. In some examples, an ingestible device is presented that includes a framework, a control device secured to the framework, and a partial power source. The partial power source may include a first digestible material secured to the framework and electrically coupled to the control device, and a second digestible material electrically isolated from and dissimilar to the first digestible material, electrically coupled to the control device, and secured to the framework. The partial power source may be configured to provide power to the control device when the first and second digestible materials come in contact with a conductive fluid. The control device, after being provided power by the first and second digestible materials, may be configured to alter conductance between the first and second digestible materials to produce a current signature through the conductive fluid that is detectable by a receiver.