A diagnostic method for monitoring changes in a fluid medium in a patient's head. The method includes positioning a transmitter at a first location on or near the patient's head, the transmitter generates and transmits a time-varying magnetic field into a fluid medium in the patient's head responsive to a first signal; positioning a receiver at a second location on or near the patient's head offset from the transmitter, the receiver generates a second signal responsive to a received magnetic field at the receiver; transmitting a time-varying magnetic field into the fluid medium in the patient's head in response to the first signal; receiving the transmitted magnetic field; generating the second signal responsive to the received magnetic field; and determining, a phase shift between the transmitted magnetic field and the received magnetic field for a plurality of frequencies of the transmitted time-varying magnetic field.

A flexible, multi-layered device for automatically sensing sweat biomarkers, storing and transmitting sensed data via wireless network to a computing device having software applications operable thereon for receiving and analyzing the sensed data. The device is functional in extreme conditions, including extremely hot temperatures, extremely cold temperatures, high salinity, high altitude, extreme pHs, and/or extreme pressures.

The present invention presents a method of fabrication for a physiological sensor with electronic, electrochemical, and chemical components. The fabrication method comprises steps for manufacturing an apparatus comprising at least one electrochemical sensor, a microcontroller, and a transceiver. The fabrication process includes the steps of substrate fabrication, circuit fabrication, pick and place, reflow soldering, electrode fabrication, membrane fabrication, sealing and curing, layer bonding, and dressing. The physiological sensor is operable to analyze biological fluids such as sweat.

A blood pressure monitor cuff is formed by stacking an outer circumferential layer arranged on a side opposite to that of a measurement site and a fluid bladder arranged on the measurement site side. The outer circumferential layer and the fluid bladder are formed of an elastomer material. Two edge portions in a lengthwise direction of the outer circumferential layer protrude in a thickness direction toward the measurement site. The fluid bladder includes a base layer that opposes the outer circumferential layer and a top layer overlapping with the base layer, and the edge portions of the base layer and the top layer are welded together forming a bladder shape. Additional sheets are welded in the thickness direction to the welded edge portions of the top layer and the base layer. The fluid bladder is arranged between the two edge portions of the outer circumferential layer in the width direction.

A wearable detection device includes a main body, a first belt body, and a second belt body. The first belt body and the second belt body are connected to two sides of the main body. The main body includes a power source, a control circuit connected to the power source, and a processor connected to the control circuit. The wearable detection device further includes a flexible circuit board and a plurality of to-be-conducted chips. The flexible circuit board is disposed in the first belt body and is connected to the main body. The plurality of to-be-conducted chips are disposed in the first belt body and are connected to the flexible circuit board. When the first belt body and the second belt body are interconnected, the to-be-conducted chip positioned at a junction point is connected.

An active implantable medical device (AIMD) is described. The AIMD has a rechargeable electrical energy power source connected to a PCB assembly for powering the medical device. The AIMD can sense biological signals from a patient, or it can have at least two electrodes that provide stimulation therapy to the patient. An inductive charging coil housed inside an elongate device enclosure is connected to the power source. The inductive charging coil has winds of an electrically conductive wire or tape that wrap around the PCB. The winds of the inductive charging coil have an upper wind portion residing above the PCB and a lower wind portion below the PCB. Opposed curved ends of the inductive charging coil winds are continuous with the upper and lower wind portions. This structure provides the inductive charging coil with a length aligned along a longitudinal axis of the PCB. In that manner, the inductive charging coil occupies a space otherwise not used in an elongate cylindrical enclosure for an AIMD.

A medical capsule is equipped with a sensor device having light emitting and light receiving elements. The sensor device can detect blood on the basis of light absorption properties of the blood. The capsule has a casing forming a recess or gap at its outer surface. The recess has a pre-selected width which represents a fixed measuring track between the light emitting and light receiving elements being arranged at opposing sides of the recess or gap when seen in its width direction. The medical capsule also has a shielding plate/layer/membrane arranged at least at or near the bottom of the recess or gap and extending along the width direction of the recess or gap preferably to exceed the recess at both sides into its width direction to prohibit emitted light from bypassing the recess via the casing material of the capsule.

Systems, devices, and methods for interfacing with biological tissue are described herein. An example electrode patch as described herein includes a flexible substrate and an electrode array arranged on the flexible substrate. The electrode array includes a plurality of electrodes, where each of the plurality of electrodes is formed of a hydrogel. Additionally, each of the plurality of electrodes defines a raised geometry. Additionally, an example system includes the electrode patch, which is configured to interface with a subject's skin, and an electronics module operably coupled to the electrode array.

An electronic device includes a housing including a first cover member, a second cover member, and a side member enclosing a space between the first cover member and the second cover member; a support member coupled to or formed integrally with the side member; a printed circuit board disposed in the space and including a biometric circuit; a first conductive portion disposed at least partially in the side member; a second conductive portion and third conductive portion disposed at least partially in the second cover member and electrically connected to the printed circuit board; and at least one conductive path disposed in the space, configured to electrically connect the biometric circuit and the first conductive portion, and formed on the support member. The biometric circuit receives a biometric signal based on the first conductive portion, the second conductive portion, the third conductive portion, and the at least one conductive path.

Provided herein is a sensor assembly including a printed circuit board including a top surface, a bottom surface and one or more sensing elements for measuring a physiologic parameter of a patient, the one or more sensing elements disposed on the top surface. The sensor assembly including an antenna coupled to the printed circuit board, the antenna coupled to the bottom surface of the printed circuit board and extending through an opening in the printed circuit board and outwardly from the top surface. The sensor assembly including a power source disposed below the printed circuit board and coupled to the printed circuit board and a case at least partially enclosing the printed circuit board, antenna, and power source, wherein the case includes a sensing opening configured to allow fluid to contact the one or more sensing element.