An intraocular pressure (IOP) includes a transmission film component, which is in direct contact with intraocular aqueous humor and configured to sense pressure fluctuations in the intraocular aqueous humor; a reflective film component set on an inner side of the transmission film component; and an adhesion layer component set on an inner layer of the reflective film component and configured to connect to an attachment device. An enclosed space formed by the reflective film component and the transmission film component constitutes a resonance chamber, which is filled with a filling medium. When a pressure in the intraocular aqueous humor is changed, the transmission film component is deformed, resulting in a change in a near-infrared (NIR) spectrum reflected by the reflective film component; the TOP is detected according to the change of the NIR spectrum.

A dielectric pad and method of fabricating a dielectric pad for improving signal-to-noise ratio and image quality in MRI procedures. The dielectric pad includes a composition of TiO.sub.2, BaTiO.sub.3, or SiC mixed with a solvent to produce a flexible and stretchable pad for MRI use. The flexible and stretchable pad is configured to conform to various body shapes, to be wrap-able, and to be wearable for MR imaging procedures.

A diagnostic manometry device comprises a catheter including a plurality of lumens, a fluid charger configured to operatively couple with the catheter, and a charging mechanism for moving fluid simultaneously from fluid pressure chambers of the plurality of fluid pressure chambers into the respective lumens of the plurality of lumens when the catheter is operatively coupled with the fluid charger. Each fluid pressure chamber of the plurality of fluid pressure chambers is configured to be in fluid communication with a respective lumen of the plurality of lumens when the catheter is operatively coupled with the fluid charger. Each pressure sensor of the plurality of pressure sensors is located and configured to measure a fluid pressure change in a respective fluid pressure chamber of the plurality of fluid pressure chambers. Additional manometry devices and methods of forming a manometry device are also disclosed.

Detection devices, systems, and methods include those for detecting analytes (e.g., volatile organic compounds (VOCs) and/or other chemical substances) from a target area of a subject's anatomy (e.g., a subject's skin, a wound on a subject, etc.). In some cases, a detector may have a detecting component that includes an analyte sensitive material applied to a substrate. The detector may be used with a pump. The detector may include a hydrophobic, gas permeable material configured to limit liquid reaching the analyte sensitive material, while allowing analytes in gaseous fluid to reach the analyte sensitive material.

A wireless circuit includes a housing having at least one opening, and sensor connected to the housing at the opening. The sensor includes a first layer having a first dimension and a second layer having a second dimension shorter than the first dimension. The second layer may be positioned entirely within the housing and a surface of said first layer may be exposed to an exterior of the housing.

A tissue treatment system and method of using the tissue treatment system determines a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen. The tissue treatment system fills a balloon with a fluid when the balloon is within a body lumen. A fluid parameter of the fluid is detected over a period of time. A parameter curve of the fluid parameter is determined. The parameter curve includes the fluid parameter versus an independent variable over the period of time. The parameter curve includes inflections that correspond to changes in the fluid parameter. Based on the inflections, the system can determine the body lumen size or the neuromodulation parameter. Other embodiments are also described and claimed.

The present invention relates to a non-invasive cardiac monitoring device that records cardiac data to infer physiological characteristics of a human, such as cardiac arrhythmia. Some embodiments of the invention allow for long-term monitoring of physiological signals. Further embodiments allow for processing of the detected cardiac rhythm signals partially on the wearable cardiac monitor device, and partially on a remote computing system. Some embodiments include a wearable cardiac monitor device for long-term adhesion to a mammal for prolonged detection of cardiac rhythm signals.

Some embodiments include processing data via an executable file on a monitor to reduce the dimensionality of the data being transmitted over the wireless network. The output of the executable file also encrypts the data before being transmitted wireless to a remote server. The remote server receives the transmitted data and makes likelihood inferences based on the recorded data.

A novel medical imaging system that is based on radio-wave signals at microwave frequencies and has unique properties. The system can be used for various diagnostic applications such as breast cancer detection, brain stroke detection, and assessment of internal bleeding (trauma emergencies).

Systems and methods for sealing a plurality of reservoirs of a microchip element with a sealing grid are provided. For example, in one embodiment, a microchip element comprises a primary substrate having a plurality of reservoirs defined therein. The microchip element also includes a single continuous sealing groove defined in the primary substrate that extends around each of the plurality of reservoirs. In addition, the microchip element includes a sealing substrate comprising a single continuous sealing protrusion extending therefrom. The single continuous sealing protrusion corresponds to and is configured to mate with the single continuous sealing groove to form a hermetic bond between the primary substrate and the sealing substrate. In this manner, the single continuous sealing groove and the single continuous sealing protrusion form a sealing grid about the plurality of reservoirs.