A device for detecting spatial differences in fluid level changes in a tissue of a patient may include a support structure for securing the device to a body part of the patient, a processing element operably connected to the support structure, a wireless networking interface operably connected to the support structure and in communication with the processing element and an external computing device via a network, a first transmission module operably connected to the support structure and in communication with the processing element, a second transmission module and a third transmission module operably connected to the support structure and in communication with the processing element. When activated, the first transmission module transmits a first time varying magnetic field through the tissue of the patient. The second and third transmission modules, which are spatially separated from one another, receive first and second versions, respectively, of the first time varying magnetic field.

In one embodiment, a method includes receiving cardiac signal segments responsively to electrical activity sensed by a first sensing electrode in contact with tissue, injecting the cardiac signal segments into a cable, which extends to a recording apparatus, the cable outputting corresponding noise-added cardiac signal segments responsively to noise acquired in the cable, training an artificial neural network to at least partially compensate for electrical noise that will be added to signals in the cable responsively to the received cardiac signal segments and corresponding noise-added cardiac signal segments, receiving a cardiac signal responsively to electrical activity sensed by a second sensing electrode, applying the trained artificial neural network to the cardiac signal yielding the cardiac signal with noise-compensation, which at least partially compensates for noise, which is not yet in the cardiac signal but will be added in the cable, and outputting the cardiac signal with noise-compensation via the cable.

Example embodiments include devices and systems that detect apnea events of a user. The device includes a first sensor configured beside the head of the user for capturing snoring sounds of the user, a second sensor configured on one finger of the user for capturing cardiovascular parameters of the user, a third sensor configured under the trunk of the user for capturing e breathing movements of the user, a data recorder that is connected with the first sensor, the second sensor and the third sensor for receiving recordings therefrom, and a clock for synchronizing the recordings in real time. The recordings include one or more breathing events including snoring events, heart rate and SPO.sub.2 conjunction spikes, and breathing movement cessations. The time periods that apnea events are impossible can be excluded according to a combination of the breathing events, and the apnea events can be detected thereafter.

A measurement sensor package and a measurement sensor reduce susceptibility to noise and enable highly accurate measurement. A measurement sensor package includes a substrate. The substrate includes a first recess including a first bottom surface on which a light emitter is mountable, and a first step surface having a first connection pad thereon, a second recess including a second bottom surface on which a light receiver is mountable, and a second step surface having a second connection pad thereon. In a direction connecting a center of the first bottom surface and a center of the second bottom surface in a plan view, the first step surface is located outward from the first bottom surface and the second step surface is located outward from the second bottom surface.

An intraluminal sensing device includes a guidewire configured to be positioned within a body lumen of a patient. The guidewire includes a core wire, a first insulative coating covering at least a portion of a circumference of the core wire, and at least two conductive traces insulated from one another and extending longitudinally along at least the portion of the length of the core wire over an outer surface of the first insulative coating. Each conductive trace conforms to the curvature of the first insulative coating. The guidewire also includes a second insulative coating covering the conductive traces along at least the portion of the length of the core wire, and a sensor in electrical communication with the at least two conductive traces and configured to obtain physiological data while positioned within the body lumen. The guidewire also includes a proximal connector in electrical communication with the conductive traces.

A patient worn sensor assembly for detecting, recording, and communicating patient vital signs can be integrated into a garment to be worn by the patient. A lead assembly can be integrated into a garment to connect electrodes in contact with the skin of a patient to a sensor assembly that collects vital sign information from the electrodes. The lead assembly can be multi-layered and can include, for example, two outer anti-static satin fabric layers as top and bottom layers, muslin fabric insulator layers adjacent to the anti-static satin fabric layers, shield layers that include muslin with silver fabric adjacent to the insulator layers, and an inner layer of fabric with conductive thread (or alternatively conductive thread not integrated with other fabrics, or a layer that is substantially composed of conductive thread).

A device for analysing and/or monitoring brain waves configured to be worn by a person, in particular during a period when the person is sleeping. The device includes a support element configured to at least partially surround the person's head so as to be held thereon, and the support element includes at least one three-dimensional fabric.

The disclosed biopotential measurement device may include a biopotential measurement circuit and a right leg drive (“RLD”) circuit coupled to the biopotential measurement circuit. The device may also include electrodes coupled to the biopotential measurement circuit and a chassis housing the biopotential measurement circuit and the RLD circuit. The chassis may include a conductive portion, coupled to the RLD circuit, that may serve as an RLD electrode for the RLD circuit. Various other methods, systems, and computer-readable media are also disclosed.

Various sensors and methods of assembling sensors are described. In some embodiments, the sensor assembly includes a first end, a body portion, and a second end. The first end can include a neck portion and a connector portion and the second end can include a flap, a first component, a neck portion, and a second component. A method is also described for sensor folding. The method can include using a circuit with an attached emitter and a detector that is separated by a portion of the circuit. The method can also include folding the portion of the circuit such that a first fold is created through the emitter and folding the portion of the circuit such that a second fold is created such that the first fold and second fold form an angle.

A system for monitoring biometric signals of a user comprising: a garment configured to be worn by the user and comprising a mounting module having an array of connection regions; a set of biometric sensors coupled to the garment and configured to communicate with the array of connection regions to receive and transmit biometric signals indicative of muscle activity of the user; and a portable control module configured to couple to the garment in a first configuration and to decouple from the garment in a second configuration and comprising: a housing comprising an array of openings; a set of contacts, each including a first region that seals at least one of the array of openings and couples to at least one of the array of connection regions in the first configuration, and an electronics subsystem coupled to the housing and in communication with a second region of each contact.