Patent classifications
C12N2795/10221
NOVEL BACTERIOPHAGE AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME
Provided is a novel bacteriophage CJ23 (KCCM11365P). In addition, the present invention relates to an antibacterial composition including the bacteriophage CJ23 (KCCM11365P) as an active ingredient. Further, provided is a method of preventing and/or treating infectious diseases by avian pathogenic Escherichia coli(APEC) in birds using the bacteriophage CJ23(KCCM11365P) or the antibacterial composition containing the bacteriophage CJ23(KCCM11365P) as an active ingredient.
METHOD FOR TREATMENT AND CONTROL OF PLANT DISEASE
Methods and compositions are provided for preventing or reducing symptoms or disease associated with Xylella fastidiosa or Xanthomonas axonopodis in a plant. The invention provides novel bacteriophages virulent to Xylella fastidiosa or Xanthomonas axonopodis, including XfaMija and XfaMijo, and further provides methods for treating or preventing Pierce's Disease or Citrus Canker in plants.
Phage therapy of pseudomonas infections
The present invention relates to bacteriophage therapy. More particularly, the present invention relates to novel bacteriophages having a high specificity against Pseudomonas aeruginosa strains, their manufacture, components thereof, compositions comprising the same and the uses thereof in phage therapy.
CRISPR-CAS10 SYSTEMS AND METHODS FOR PHAGE GENOME EDITING
The present disclosure relates to CRISPR-Cas10 systems and methods for phage genome editing.
RECOMBINANT K1-5 BACTERIOPHAGES AND USES THEREOF
The present disclosure provides compositions including recombinant K1-5 bacteriophages, methods for making the same, and uses thereof. The recombinant K1-5 bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
BACTERIOPHAGE RECOMBINATION FOLLOWED BY BLOCKAGE OF NON-RECOMBINANT BACTERIOPHAGE REPLICATION
The present disclosure provides methods and kits for generating recombinant bacteriophage genomes. Specifically, the present technology provides methods of integrating a heterologous nucleic acid sequence into a bacteriophage DNA genome, and isolating recombinant bacteriophages that express the heterologous nucleic acid sequence.
BACTERIOPHAGES WITH IMPROVED ANTIMICROBIAL ACTIVITY
Provided herein are bacteriophages engineered to express an exopolysaccharide (EPS) depolymerase for treating bacterial infections. In some embodiments, the EPS depolymerase comprises alginate lyase. Also envisioned within the scope of the invention are compositions comprising one or more of the bacteriophages, methods for treating bacterial infections, and kits comprising the compositions described herein.
Polypeptides specific to Klebsiella pneumoniae capsular type strains
The present invention relates to novel bacteriophages specific to Klebsiella pneumoniae strains, and compositions comprising the same. Particularly, polypeptides and their coding nucleic acid molecule of the novel bacteriophages are provided. The invention also relates to applications of the novel bacteriophages and the polypeptides in the detection/treatment/prevention of infection caused by Klebsiella pneumoniae strains. Development of immunogen and vaccine on the basis of the polypeptides are also provided.
Bacteriophage and antibacterial composition comprising the same
Provided is a novel bacteriophage CJ23 (KCCM11365P). In addition, the present invention relates to an antibacterial composition including the bacteriophage CJ23 (KCCM11365P) as an active ingredient. Further, provided is a method of preventing and/or treating infectious diseases by avian pathogenic Escherichia coli (APEC) in birds using the bacteriophage CJ23 (KCCM11365P) or the antibacterial composition containing the bacteriophage CJ23 (KCCM11365P) as an active ingredient.
PHAGE THERAPY OF E COLI INFECTIONS
The present invention relates to bacteriophage therapy. More particularly, the present invention relates to novel bacteriophages having a high specificity against Escherichia coli strains, their manufacture, components thereof, compositions comprising the same and the uses thereof in phage therapy.