An aqueous oral care solution, a kit that includes such solution, a method of making such solution, a method of using such solution (e.g., a method of providing fluoride to a patient's tooth surface), and a tooth surface having a coating derived from the aqueous oral care solution, wherein the oral care solution includes: silver cations; thiocyanatc anions provided by a thiocyanatc source comprising Ca(SCN)2; fluoride anions; and water; wherein the molar ratio of silver to thiocyanatc ions is up to 0.40:1, and water is up to 57 wt-%, based on the total weight of the solution.

An aqueous oral care solution, a kit that includes such solution, a method of making such solution, a method of using such solution (e.g., a method of providing fluoride to a patient's tooth surface), and a tooth surface having a coating derived from the aqueous oral care solution, wherein the oral care solution includes: silver cations; thiocyanatc anions provided by a thiocyanatc source comprising Ca(SCN)2; fluoride anions; and water; wherein the molar ratio of silver to thiocyanatc ions is up to 0.40:1, and water is up to 57 wt-%, based on the total weight of the solution.

An intraoral applicator device is described herein that is configured to transfer medicament from the applicator to the gums of a patient. The device and methods of use may assist in topically applying medicament e.g. a topical anaesthetic to the gums of a patient without the need for or use of needles or syringes. In one embodiment, the intraoral applicator device may comprise a body with a shape and configuration that generally conforms with at least part of the shape of the teeth and gums of a patient's oral cavity. The device further comprises a holder portion, the holder portion comprising a frame, the frame being configured to clamp over the teeth about a region of the patient's oral cavity such that, when fitted to the patient's oral cavity, at least a part of the holder portion is configured to be held between the patient's teeth when the patient bites their jaws together, the holder portion also gripping at least part of the body. Methods of delivering medicament to at least a portion of the gums of a patient in need thereof using the above device are also described.

An intraoral applicator device is described herein that is configured to transfer medicament from the applicator to the gums of a patient. The device and methods of use may assist in topically applying medicament e.g. a topical anaesthetic to the gums of a patient without the need for or use of needles or syringes. In one embodiment, the intraoral applicator device may comprise a body with a shape and configuration that generally conforms with at least part of the shape of the teeth and gums of a patient's oral cavity. The device further comprises a holder portion, the holder portion comprising a frame, the frame being configured to clamp over the teeth about a region of the patient's oral cavity such that, when fitted to the patient's oral cavity, at least a part of the holder portion is configured to be held between the patient's teeth when the patient bites their jaws together, the holder portion also gripping at least part of the body. Methods of delivering medicament to at least a portion of the gums of a patient in need thereof using the above device are also described.

A sterile, disposable pre-pasted toothbrush having a toothpaste composition containing an anti-cavity agent and a numbing agent, with the toothpaste composition distributed over extra soft bristles and arranged on a small bristle head, with the toothbrush and toothpaste composition sterilized by an ozone treatment, to produce a disposable toothbrush particularly suited for patients with compromised immune systems.

A sterile, disposable pre-pasted toothbrush having a toothpaste composition containing an anti-cavity agent and a numbing agent, with the toothpaste composition distributed over extra soft bristles and arranged on a small bristle head, with the toothbrush and toothpaste composition sterilized by an ozone treatment, to produce a disposable toothbrush particularly suited for patients with compromised immune systems.

The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active agent, and pharmaceutically acceptable excipient(s), and a process of preparing such compositions. Further, the present application relates to method of using topical compositions for the treatment of skin disorders such as acne, rosacea, psoriasis etc.

The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active agent, and pharmaceutically acceptable excipient(s), and a process of preparing such compositions. Further, the present application relates to method of using topical compositions for the treatment of skin disorders such as acne, rosacea, psoriasis etc.

The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active agent, and pharmaceutically acceptable excipient(s), and a process of preparing such compositions. Further, the present application relates to method of using topical compositions for the treatment of skin disorders such as acne, rosacea, psoriasis etc.

The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active agent, and pharmaceutically acceptable excipient(s), and a process of preparing such compositions. Further, the present application relates to method of using topical compositions for the treatment of skin disorders such as acne, rosacea, psoriasis etc.