The present invention relates to an innovative biological prostheses, equipped with a drainage system, designed for all surgical applications where there is any risk of hematomas or seromas, which not only allows to minimize adverse events arising from its application, but allows also to improve the effectiveness of the functional reconstruction. The prosthesis of the present invention is a surgical prosthesis made of animal derived collagen having a peripheral outline and a drainage portion comprising a plurality of drainage holes which are located in one or more independent groups each of which has a regular body-centered polygon layout.

An arrangement includes: a plurality of mesh tubes arranged in parallel and extending along an axial direction, each mesh tube of the plurality of mesh tubes having a mesh tube length in the axial direction; and a first mesh sheet having a first surface. The plurality of mesh tubes is disposed on the first surface. The arrangement provides structural support to surrounding tissues upon placement of the arrangement into a human body.

A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

A heart valve repair device, comprising an atrial-fixation member having an expandable mesh configured to have oval or circular shape in a deployed configuration, the atrial-fixation member defining a central lumen; and a baffle extending from a portion of the atrial-fixation member, the baffle having an anterior portion with a smooth, atraumatic surface configured to coapt with at least a portion of one or more native leaflets of a native heart valve, a posterior portion configured to engage and displace at least a portion of another native leaflet of the native heart valve, wherein the baffle extends radially inward from the atrial-fixation member into the central lumen to approximate a closed position of the displaced native leaflet.

A tendon repair implant for treatment of a partial thickness tear in the supraspinatus tendon of the shoulder is provided. The implant may incorporate features of rapid deployment and fixation by an arthroscopic means approach that compliment current procedures; tensile properties that result in desired sharing of anatomical load between the implant and native tendon during rehabilitation; selected porosity and longitudinal pathways for tissue in-growth; sufficient cyclic straining of the implant in the longitudinal direction to promote remodeling of new tissue to tendon-like tissue; and, may include a bioresorbable construction to provide transfer of additional load to new tendon-like tissue and native tendon over time.

This three-dimensional knitted textile insert is obtained in a single step by warp knitting technology, on a double-needle Raschel machine or on a crocheting machine. It includes in the production direction at least two tubes extending parallel to one another, and separated from one another by a binding area at the level of which the sheets resulting from the knitting are interlinked.

The present invention relates to a prosthesis (1) for repairing an inguinal hernia defect comprising: a piece (2) of biocompatible material having a preformed three-dimensional shape, including: a first portion (3) forming a partial spherical cap surface (8) shaped and dimensioned so as to substantially conform to the shape of the anterior abdominal wall, a second portion (4) extending from an inferior edge of said first portion and forming a wavy-shaped wall (9), shaped and dimensioned so as to substantially conform to the shape of the psoas muscle, characterized in that said piece (2) further comprises: a third portion (5) forming an arched part (10) extending longitudinally in the inferior direction from a medial inferior corner (3a) of said first portion, said arched part extending radially substantially in the front direction, said third portion being intended to face the medial inferior area of the inguinal anatomy.

A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

Graft materials and devices for surgical breast procedures, as well as methods of making graft devices, are described.

Methods for producing crosslinked tissue matrices, crosslinked tissue matrices produced by such methods, as well as tissue products comprising such tissue matrices are disclosed. The methods comprise (1) dehydrating a collagen-containing tissue matrix to form a dehydrated collagen-containing tissue matrix; and (2) irradiating the dehydrated collagen-containing tissue matrix such that at least a portion of the dehydrated collagen-containing tissue matrix is crosslinked.