A device for stabilizing a lumen in an open position having a core with a longitudinal axis along the length of the core, and support elements that can be bristles, fibers, or discs, secured to the core, extending radially outward from the core, and having ends that can contact and hold open a lumen, while maintaining the position of the device in the lumen.

An exemplary process includes determining a desired pore size, selecting an initial pore size greater than the target pore size, manufacturing a porous structure with the initial pore size, forging the porous structure to form a forged part having the desired pore size, and forming an orthopedic device from the forged part.

A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier.

An implantable containment apparatus for receiving and retaining a plurality of cells for insertion into a patient, such as into a tissue bed, is disclosed. The device includes a chamber having structural spacers therein to maintain an average distance between the first interior surface and the second interior surface of the chamber and to define at least one reservoir space for the placement of cells within the chamber.

Provided is an intraocular lens including: an optic portion; and a haptic portion extending from the optic portion, wherein a pattern having ridges and grooves is formed on at least one of the optic portion and the haptic portion, and each of the grooves has a nanostructure roughness. Provided also is a method of manufacturing an intraocular lens, the method including: seating an object to be processed including an optic portion and at least one haptic portion extending from the optic portion, processing a predetermined pattern for guiding cells by performing laser irradiation on the haptic portion and the optic portion, forming grooves having a nanostructure surface roughness in the predetermined pattern formed by laser beams, and the surface of each of the grooves has an average roughness Ra less than 200 nm.

The present invention relates to the field of implants. In particular, the present invention relates to an implant for tissue reconstruction which comprises a scaffold structure that includes a void system for the generation of prevascularized connective tissue with void spaces for cell and/or tissue transplantation. Moreover, the present invention relates to a method of manufacturing such an implant, to the internal architecture of such an implant, to a removal tool for mechanical removal of space-occupying structures from such an implant, to a kit comprising such an implant and such a removal tool, to a removal device for the removal of superparamagnetic or ferromagnetic space-occupying structures from such an implant, as well as to a guiding device for providing feedback to a surgeon during the procedure of introducing transplantation cells into the void spaces generated upon removal of space-occupying structures from such an implant.

The present invention relates to a synthetic prosthesis for tissue reinforcement comprising: a porous knit made from a monofilament of a synthetic biocompatible material, said knit defining two opposite faces, a first face and a second face, a synthetic non porous biodegradable film comprising at least a copolymer of at least -caprolactone, said film covering at least part of said first face, a synthetic biodegradable binder bonding said film to said first face, said binder comprising at least a polymer of -caprolactone, wherein said second face of said porous knit is left open to cell colonization. The invention also relates to a method for forming such a prosthesis.

The present invention relates to a synthetic prosthesis for tissue reinforcement comprising: a porous knit made from a monofilament of a synthetic biocompatible material, said knit defining two opposite faces, a first face and a second face, a synthetic non porous biodegradable film comprising at least a copolymer of at least -caprolactone, said film covering at least part of said first face, a synthetic biodegradable binder bonding said film to said first face, said binder comprising at least a polymer of -caprolactone, wherein said second face of said porous knit is left open to cell colonization. The invention also relates to a method for forming such a prosthesis.

A patch for repairing a hernia defect including a patch body that is reducible into a small configuration for delivery through a narrow incision or cannula into a patient. A support member assists in unfurling the patch body from the small configuration into an expanded configuration. A sleeve releasably mounts the support member to the patch body.

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a filament and a membrane arranged about the filament. The membrane may be configured to contain fragments of the filament and maintain structure of the membrane in response to the fracture or degradation of the filament.